Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | STK10 | O94804 | 1/20 | 0.31 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564440 | 0.80 | TP53 (0.36) | FABP3FABP4ALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL9138237 | 0.79 | HSD11B1 (0.41) | ALDH1A1STK10SLKCYP2A6 | |
| SCHEMBL17999104 | 0.77 | ACHE (0.37) | FABP3FABP4CES2CES1NFE2L2 | |
| SCHEMBL436469 | 0.74 | NOTUM (0.38) | MAPK14CYP1A2CYP2A6 | |
| SCHEMBL9649089 | 0.74 | TSHR (0.32) | — | |
| SCHEMBL435140 | 0.74 | AHR (0.40) | ALDH1A1MAPTMAPK14 | |
| SCHEMBL7507597 | 0.74 | GABRP (0.42) | — | |
| SCHEMBL17514679 | 0.74 | ALDH1A1 (0.33) | CES2CES1ALDH1A1 | |
| SCHEMBL6927659 | 0.73 | NISCH (0.40) | MAPK14 | |
| SCHEMBL1205892 | 0.72 | TAAR1 (0.44) | CES2CES1MAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150158-A | Oxadiazindione derivatives useful as insecticides | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |