Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL208216 | 1.00 | MAPT (0.33) | MAPTTSHRFFAR3TP53CA2 | |
| Bicarbonate SCHEMBL2774047 | 0.97 | MAPT (0.33) | MAPTTSHRFFAR3TP53CA2 | |
| SCHEMBL124121 | 0.88 | — | — | |
| Benzene SCHEMBL190107 | 0.86 | TSHR (0.35) | MAPTTSHR | |
| Bicarbonate SCHEMBL28900979 | 0.82 | CA2 (0.42) | MAPTTSHRCA2MAPK1TDP1 | |
| Bicarbonate SCHEMBL27232679 | 0.80 | TSHR (0.35) | MAPTTSHRFFAR3TP53CA2 | |
| Bicarbonate SCHEMBL29135929 | 0.78 | FFAR3 (0.33) | MAPTTSHRFFAR3TP53CA2 | |
| Bicarbonate SCHEMBL28959796 | 0.78 | FFAR3 (0.33) | MAPTTSHRFFAR3TP53CA2 | |
| Bicarbonate SCHEMBL28587396 | 0.74 | FFAR3 (0.35) | TSHRFFAR3CA2MAPK1CHRM1 | |
| SCHEMBL25435789 | 0.72 | MAPT (0.41) | MAPTTSHRFFAR3TP53CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396071-A | Delivery particles with high core to wall ratio | 恩盖普有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117177808-A | Delivery particles with high core to wall ratio | 恩盖普有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-116583587-A | Consumer product comprising delivery particles with high core to wall ratio | 宝洁公司 | 2023-08-11 | — | — | CN | claimed |
| CN-116546955-A | Consumer product comprising delivery particles with high core to wall ratio | 宝洁公司 | 2023-08-04 | — | — | CN | claimed |
| CN-110891986-B | Process for preparing ethylene-vinyl acetate copolymer | LG化学株式会社 | 2023-07-18 | — | — | CN | claimed |
| CN-115715301-A | Process for preparing a composition comprising at least a mixture of at least one peroxydicarbonate and at least one peroxyester | 阿科玛法国公司 | 2023-02-24 | — | — | CN | claimed |
| CN-115702172-A | Aqueous composition comprising at least one peroxydicarbonate and at least one peroxyester in the form of an emulsion | 阿科玛法国公司 | 2023-02-14 | — | — | CN | claimed |
| CN-111936533-B | Ethylene-vinyl acetate copolymer and method for producing the same | LG化学株式会社 | 2022-09-06 | — | — | CN | claimed |
| CN-114341202-A | Treatment process based on polymeric dispersions using specific organic peroxides | 阿科玛法国公司 | 2022-04-12 | — | — | CN | claimed |
| EP-3814417-A1 | (METH)ACRYLIC COMPOSITION, COMPOSITE MATERIAL OBTAINED FROM SUCH A COMPOSITION, METHOD FOR PRODUCING SAME AND USES THEREOF | ARKEMA FRANCE (FR) | 2021-05-05 | — | — | EP | claimed |
| US-6995221-B2 | Stable and pure organic peroxides produced outside of reactors by forming an aqueous emulsion of the peroxy reactants; addition polymers are solvent- and plasticizer-free and of high quality | OXY VINYLS, L.P. (US) | 2006-02-07 | — | — | US | claimed |
| US-20040249097-A1 | Stable and pure organic peroxides produced outside of reactors by forming an aqueous emulsion of the peroxy reactants; addition polymers are solvent- and plasticizer-free and of high quality | OXY VINYLS, L.P. | 2004-12-09 | — | — | US | claimed |
| US-20040215034-A1 | SUCH AS DIETHYL PEROXYDICARBONATE; HOMOGENATION; SOLVENT/PLASTICIZER-FREE | OXY VINYLS, LP | 2004-10-28 | — | — | US | claimed |
| WO-2000031149-A1 | RADICAL-CURABLE ADHESIVE COMPOSITIONS, REACTION PRODUCTS OF WHICH DEMONSTRATE SUPERIOR RESISTANCE TO THERMAL DEGRADATION | LOCTITE CORPORATION (US) | 2000-06-02 | — | — | WO | claimed |
| WO-2000031165-A1 | RADICAL-CURABLE ADHESIVE COMPOSITIONS, REACTION PRODUCTS OF WHICH DEMONSTRATE SUPERIOR RESISTANCE TO THERMAL DEGRADATION | LOCTITE CORPORATION (US) | 2000-06-02 | — | — | WO | claimed |
| EP-0659194-A1 | PROCESS FOR (CO)POLYMERIZING VINYL MONOMERS. | KAYAKU NOURY CORP (JP) | 1995-06-28 | — | — | EP | claimed |
| EP-0295947-B1 | Gas permeable contact lens and method and materials for its manufacture | OCULAR TECHNOLOGIES INC (US) | 1994-12-21 | — | — | EP | claimed |
| WO-1994006269-A1 | PROCESS FOR (CO)POLYMERIZING VINYL MONOMERS | KAYAKU AKZO CORPORATION (JP) | 1994-03-17 | — | — | WO | claimed |
| US-4820747-A | ACRYLATED CROSSLINKED POLYSILOXANES FORM HARD, HYDROPHILIC, DISPOSABLE, EXTENDED-WEAR LENSES | OCULAR TECHNOLOGIES, INC. (US) | 1989-04-11 | — | — | US | claimed |
| EP-0295947-A2 | Gas permeable contact lens and method and materials for its manufacture | OCULAR TECHNOLOGIES INC. (US) | 1988-12-21 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040215034-A1 | SUCH AS DIETHYL PEROXYDICARBONATE; HOMOGENATION; SOLVENT/PLASTICIZER-FREE | HAO2, GPX4, HDHD5 | MAPT 3301/4885TSHR 3292/4885FFAR3 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.