Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.45 |
| ▸ | CES2 | O00748 | 7/20 | 0.43 |
| ▸ | CES1 | P23141 | 6/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15041013 | 0.76 | TTR (0.65) | TTRHTR2BTNKS | |
| SCHEMBL22645256 | 0.74 | MAPT (0.51) | HDAC1HDAC8HDAC6PTPN1ALOX5 | |
| SCHEMBL20793652 | 0.73 | GPR35 (0.51) | TTRDYRK1A | |
| SCHEMBL15071004 | 0.72 | TTR (0.59) | TTRCES2CES1HTR2BTNKS | |
| SCHEMBL783749 | 0.72 | NR4A1 (0.50) | PTPRFPTPN2PTPN1ALOX5CYSLTR1 | |
| SCHEMBL7056984 | 0.71 | PRMT1 (0.44) | TTRHTR2B | |
| SCHEMBL9450964 | 0.71 | MEN1 (0.47) | TTRPTPRFPTPN2PTPN1CYSLTR1 | |
| SCHEMBL26317302 | 0.70 | NPC1 (0.59) | TTRHTR2BDYRK1A | |
| SCHEMBL12180808 | 0.70 | CES2 (0.58) | TTRCES2CES1TNKS | |
| SCHEMBL11554090 | 0.69 | PTPN1 (0.60) | TTRPTPRFPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076634-A | Composition for antifriction material | KORSHAK VASILY VLADIMIROVICH | 1978-02-28 | — | — | US | disclosed |