Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832723 | 0.82 | — | — | |
| SCHEMBL6317714 | 0.74 | CA2 (0.32) | POLB | |
| SCHEMBL7671774 | 0.73 | IMPDH2 (0.37) | IMPDH2 | |
| SCHEMBL10400366 | 0.72 | CYP3A4 (0.39) | XDHPOLBGABRA1GABRB2KDM4E | |
| SCHEMBL8623552 | 0.72 | ALOX15 (0.47) | POLBALDH1A1HPGD | |
| SCHEMBL9485968 | 0.69 | GABRA1 (0.41) | XDHPOLBGABRA1GABRB2KDM4E | |
| SCHEMBL5831274 | 0.67 | ALDH1A1 (0.33) | XDHIMPDH2POLBGABRA1GABRB2 | |
| SCHEMBL3437109 | 0.67 | — | — | |
| SCHEMBL1624906 | 0.66 | TDP1 (0.48) | POLBALDH1A1MAPTAKR1B1PPARG | |
| SCHEMBL7077104 | 0.65 | XDH (0.40) | XDHPOLBGABRA1GABRB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4170711-A | FLAME RETARDANTS FOR POLYESTERS, POLYCARBONATES, AND POLYURETHANES | GENERAL ELECTRIC COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| US-4170711-A | FLAME RETARDANTS FOR POLYESTERS, POLYCARBONATES, AND POLYURETHANES | GENERAL ELECTRIC COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| US-3989531-A | POLYSTYRENE | GENERAL ELECTRIC COMPANY (US) | 1976-11-02 | — | — | US | disclosed |
| US-3989531-A | POLYSTYRENE | GENERAL ELECTRIC COMPANY (US) | 1976-11-02 | — | — | US | disclosed |
| US-3956403-A | Brominated biphenols | GENERAL ELECTRIC COMPANY (US) | 1976-05-11 | — | — | US | disclosed |