Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 8/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455255 | 0.86 | CES1 (0.44) | CES1SRCCES2MAPK1HIF1A | |
| SCHEMBL5913016 | 0.86 | CES1 (0.45) | CES1SRCCES2MAPK1HIF1A | |
| SCHEMBL7945147 | 0.82 | CES1 (0.49) | CES1SRCCES2MAPK1HIF1A | |
| SCHEMBL504243 | 0.79 | RECQL (0.45) | CES1CES2LMNAMAPTALDH1A1 | |
| SCHEMBL449214 | 0.79 | CA1 (0.38) | CES1PTPN1LMNAMAPTHSD11B1 | |
| SCHEMBL36097 | 0.79 | CES1 (0.59) | CES1SRCCES2MAPK1HIF1A | |
| SCHEMBL1255415 | 0.78 | LMNA (0.50) | CES1SRCCES2LMNAMAPT | |
| SCHEMBL5574740 | 0.78 | CES1 (0.49) | CES1SRCCES2HIF1ALMNA | |
| SCHEMBL503385 | 0.77 | CES1 (0.42) | CES1CES2PTPN1 | |
| SCHEMBL452943 | 0.77 | KMT2A (0.38) | CES1ALDH1A1MEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000193-A1 | Coating compositions | BAYER AG (DE) | 1979-01-10 | — | — | EP | disclosed |