SCHEMBL449214

SCHEMBL449214

O=C(c1ccccc1)C(CO)(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.38
CA2 P00918 8/20 0.38
MMP1 P03956 4/20 0.38
MMP2 P08253 4/20 0.38
MMP9 P14780 4/20 0.38
MMP8 P22894 4/20 0.38
MMP13 P45452 4/20 0.38
CES1 P23141 2/20 0.38
PTPN1 P18031 2/20 0.34
NR1I2 O75469 1/20 0.33
NR1H2 P55055 1/20 0.33
RORC P51449 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KAT6A Q92794 1/20 0.32
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL455255 0.86 CES1 (0.44) CA1CA2CES1PTPN1LMNA
SCHEMBL11579454 0.79 CES1 (0.42) CES1PTPN1LMNAMAPTHSD11B1
SCHEMBL5913016 0.78 CES1 (0.45) CES1PTPN1MAPTKAT6A
SCHEMBL21874985 0.75 CES1 (0.39) CA1CA2MMP1MMP2MMP9
SCHEMBL452943 0.75 KMT2A (0.38) CES1RORCKAT6AHSD11B1
SCHEMBL7945147 0.74 CES1 (0.49) CES1PTPN1LMNAMAPT
SCHEMBL1346042 0.73 CA1 (0.39) CA1CA2MMP1MMP2MMP9
SCHEMBL504243 0.72 RECQL (0.45) CES1LMNAMAPTNPSR1HSD11B1
SCHEMBL36097 0.71 CES1 (0.59) CES1LMNANPSR1
SCHEMBL5574740 0.70 CES1 (0.49) CES1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3010943-B1 CURABLE COMPOSITION, FILM, AND METHOD OF PRODUCING FILM CANON KK (JP) 2024-04-03 EP disclosed
US-11332597-B2 Photo-curable composition and patterning method using the same CANON KABUSHIKI KAISHA (JP) 2022-05-17 US disclosed
EP-2841255-B1 RESIN PRODUCTION METHOD AND RESIN PRODUCTION APPARATUS CANON KK (JP) 2020-05-13 EP disclosed
US-20200123343-A1 PHOTO-CURABLE COMPOSITION AND PATTERNING METHOD USING THE SAME CANON KK (JP) 2020-04-23 US disclosed
US-10472445-B2 Photocurable composition and method for manufacturing film CANON KABUSHIKI KAISHA (JP) 2019-11-12 US disclosed
US-10421853-B2 Photosensitive gas generating agent and photocurable composition CANON KABUSHIKI KAISHA (JP) 2019-09-24 US disclosed
EP-2907156-B1 IMPRINTING METHOD AND CURABLE COMPOSITION FOR IMPRINTING CANON KK (JP) 2019-04-10 EP disclosed
US-10233274-B2 Curable composition and patterning method using the same CANON KABUSHIKI KAISHA (JP) 2019-03-19 US disclosed
US-10208183-B2 Curable composition, film, and method of producing film CANON KABUSHIKI KAISHA (JP) 2019-02-19 US disclosed
EP-2760894-B1 PHOTO-CURABLE COMPOSITION AND PATTERNING METHOD USING THE SAME CANON KK (JP) 2018-12-12 EP disclosed
EP-2372405-A1 Lens and method for producing lens Canon Kabushiki Kaisha (JP) 2011-10-05 EP disclosed
WO-2011027845-A1 MANUFACTURING METHOD FOR PLASTIC MEMBER AND PLASTIC MEMBER CANON KABUSHIKI KAISHA (JP) 2011-03-10 WO disclosed
US-20100273109-A1 METHOD FOR PRODUCING OPTICAL PART CANON KABUSHIKI KAISHA (JP) 2010-10-28 US disclosed
EP-2243622-A2 Method for producing optical part CANON KABUSHIKI KAISHA (JP) 2010-10-27 EP disclosed
US-20070275327-A1 PHOTOSENSITIVE RESIN COMPOSITION, RESIST PATTERN FORMING METHOD, SUBSTRATE PROCESSING METHOD, AND DEVICE MANUFACTURING METHOD CANON KABUSHIKI KAISHA (JP) 2007-11-29 US disclosed
EP-1011029-B1 Radiation-sensitive resin composition JSR CORP (JP) 2006-08-30 EP disclosed
US-20050221222-A1 Photosensitive resin composition, resist pattern forming method, substrate processing method, and device manufacturing method CANON KABUSHIKI KAISHA (JP) 2005-10-06 US disclosed
US-6337171-B1 AS A RESIST APPLICABLE TO FAR ULTRAVIOLET RAYS SUCH AS A KRF EXCIMER LASER, CHARGED PARTICLE RAYS SUCH AS ELECTRON BEAMS, AND X-RAYS JSR CORPORATION (JP) 2002-01-08 US disclosed
US-6280900-B1 RADIATION SENSITIVE COMPOSITION WITH ALKALINE DEVELOPER SOLUBLE IN POLYMER COATED ON SUBSTRATE JSR CORPORATION (JP) 2001-08-28 US disclosed
EP-1011029-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2000-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10421853-B2 Photosensitive gas generating agent and photocurable composition PFN1, PFAS, FRG1 CA1 3547/4885CA2 1047/4885MMP1 4525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.