Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1159241 | 0.96 | CNR2 (0.38) | TSHRCNR2PLA2G4BTHRBCNR1 | |
| SCHEMBL7163680 | 0.87 | KDM4E (0.38) | TSHR | |
| SCHEMBL1158609 | 0.82 | MCHR1 (0.38) | TSHRCNR2THRATHRBCNR1 | |
| SCHEMBL7165340 | 0.80 | ENPP2 (0.39) | TSHRALOX5 | |
| SCHEMBL1159080 | 0.77 | CYP1A2 (0.39) | CNR2CNR1 | |
| SCHEMBL1159239 | 0.74 | NR5A1 (0.40) | TSHRCNR2PLA2G4BCNR1 | |
| SCHEMBL27773209 | 0.73 | LTA4H (0.53) | TSHRCNR2 | |
| SCHEMBL2839258 | 0.72 | CYP1A2 (0.49) | CNR2CNR1 | |
| SCHEMBL1159122 | 0.71 | CNR2 (0.41) | CNR2CNR1 | |
| SCHEMBL1021211 | 0.70 | TSHR (0.63) | TSHRSMPD1GGPS1PLA2G4BTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11866590-B2 | Diisocyanate-based radical polymerizable silane coupling compound having an urethane bond | KABUSHIKI KAISHA SHOFU (JP) | 2024-01-09 | — | — | US | disclosed |
| EP-2979679-B1 | CURABLE COMPOSITION FOR DENTAL USE | KURARAY NORITAKE DENTAL INC (JP) | 2023-11-29 | — | — | EP | disclosed |
| WO-2023182514-A1 | ADHESIVE COMPOSITION FOR STEREOLITHOGRAPHIC ARTICLE AND NON-STEREOLITHOGRAPHIC ARTICLE | クラレノリタケデンタル株式会社 | 2023-09-28 | — | — | WO | disclosed |
| EP-2216349-B1 | USE OF A PHENOL TYPE COMPOUND IN A DENTAL CHEMICAL POLYMERIZATION CATALYST WITH IMPROVED POLYMERIZING ACTIVITY | TOKUYAMA DENTAL CORP (JP) | 2023-09-20 | — | — | EP | disclosed |
| WO-2023120611-A1 | CURABLE DENTAL COMPOSITION | クラレノリタケデンタル株式会社 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023120610-A1 | DENTAL CURABLE COMPOSITION | クラレノリタケデンタル株式会社 | 2023-06-29 | — | — | WO | disclosed |
| US-11607370-B2 | Dental composition | KURARAY NORITAKE DENTAL INC. (JP) | 2023-03-21 | — | — | US | disclosed |
| US-20210395532-A1 | DIISOCYANATE-BASED RADICAL POLYMERIZABLE SILANE COUPLING COMPOUND HAVING AN URETHANE BOND | KABUSHIKI KAISHA SHOFU (JP) | 2021-12-23 | — | — | US | disclosed |
| US-11173100-B2 | Multi-part dental cement | KURARAY NORITAKE DENTAL INC. (JP) | 2021-11-16 | — | — | US | disclosed |
| EP-3530258-B1 | MULTI-PACK TYPE DENTAL CEMENT | KURARAY NORITAKE DENTAL INC (JP) | 2021-08-18 | — | — | EP | disclosed |
| US-6759449-B2 | NONCROSSLINKING POLYMETHYL METHACRYLATE AND POLYETHYL METH-ACRYLATE SPHERICAL FILLER, UNSATURATED ACID FUNCTIONALIZED MONOMER AND POLYMERIZATION INITIATOR | TOKUYAMA DENTAL CORPORATION (JP) | 2004-07-06 | — | — | US | disclosed |
| US-20040006154-A1 | Deantal catalyst for chemical polymerization and use thereof | IBARAGI KAZUYA (JP) | 2004-01-08 | — | — | US | disclosed |
| US-6660784-B2 | Adhesives; mixture of peroxy compounds and tetraphenylborate as catalyst | TOKUYAMA CORPORATION (JP) | 2003-12-09 | — | — | US | disclosed |
| US-20030050359-A1 | Dental adhesive composition | TOKUYAMA DENTAL CORPORATION (JP) | 2003-03-13 | — | — | US | disclosed |
| EP-1249221-A1 | DENTAL ADHESIVE COMPOSITION | Tokuyama Dental Corporation (JP) | 2002-10-16 | — | — | EP | disclosed |
| US-20020132951-A1 | Dental catalyst for chemical polymerization and use thereof | TOKUYAMA CORPORATION | 2002-09-19 | — | — | US | disclosed |
| EP-1190695-A1 | Catalyst for chemical polymerization of dental materials | TOKUYAMA CORPORATION (JP) | 2002-03-27 | — | — | EP | disclosed |
| EP-0738928-B1 | Visible-ray polymerization initiator and visible-ray polymerizable composition | TOKUYAMA CORP (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5744511-A | BLEND OF COUMARIN DYES, ACID GENERATOR AND ARYL BORATE | TOKUYAMA CORPORATION (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0738928-A2 | Visible-ray polymerization initiator and visible-ray polymerizable composition | TOKUYAMA CORPORATION (JP) | 1996-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006154-A1 | Deantal catalyst for chemical polymerization and use thereof | MPO, DBN1, BRD1 | TSHR 3239/4885SMPD1 3489/4885CNR2 4597/4885 |
| US-11607370-B2 | Dental composition | ITGAL, ITGA1, ITGB3 | TSHR 4827/4885SMPD1 3594/4885CNR2 4581/4885 |
| US-11173100-B2 | Multi-part dental cement | ASH2L, CAD, SETDB1 | TSHR 4621/4885SMPD1 2544/4885CNR2 4413/4885 |
| US-11866590-B2 | Diisocyanate-based radical polymerizable silane coupling compound having an urethane bond | CAD, DCLRE1A, STIM1 | TSHR 4002/4885SMPD1 3524/4885CNR2 3007/4885 |
| US-20030050359-A1 | Dental adhesive composition | CAD, ASIC1, CD44 | TSHR 4226/4885SMPD1 4679/4885CNR2 4860/4885 |
| US-20210395532-A1 | DIISOCYANATE-BASED RADICAL POLYMERIZABLE SILANE COUPLING COMPOUND HAVING AN URETHANE BOND | CAD, DCLRE1A, STIM1 | TSHR 4002/4885SMPD1 3524/4885CNR2 3007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.