Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 11/20 | 0.38 |
| ▸ | RORA | P35398 | 5/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285441 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1MAPTHTTHPGD | |
| SCHEMBL11312312 | 0.79 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL11724290 | 0.73 | ABCB1 (0.41) | KDM4EALDH1A1MEN1KMT2ALOXL2 | |
| SCHEMBL11068290 | 0.72 | ABCB1 (0.40) | KDM4EALDH1A1MAPTLOXL2TSHR | |
| SCHEMBL11063088 | 0.72 | HTR1A (0.40) | TSHRMAPK1 | |
| Oxalic Acid SCHEMBL11064143 | 0.71 | MEN1 (0.40) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11246816 | 0.71 | HTR6 (0.35) | KDM4EALDH1A1MEN1KMT2ALOXL2 | |
| SCHEMBL11225702 | 0.71 | HTR6 (0.38) | KDM4EALDH1A1MEN1KMT2ALOXL2 | |
| Hydrochloric Acid SCHEMBL11227227 | 0.70 | HTR6 (0.38) | KDM4EALDH1A1MEN1KMT2ALOXL2 | |
| SCHEMBL11283090 | 0.70 | ADRB2 (0.48) | KDM4EALDH1A1MAPTHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070470-A | BENCYCLOAMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | claimed |