Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795415 | 0.83 | P2RX3 (0.31) | P2RX3 | |
| SCHEMBL15012438 | 0.76 | MMP9 (0.37) | GAACYP3A4 | |
| SCHEMBL17857553 | 0.70 | ALDH1A1 (0.50) | KDM4EALDH1A1MEN1MAPTPKM | |
| SCHEMBL2851785 | 0.69 | ALDH1A1 (0.41) | GAAKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL7645942 | 0.68 | NPSR1 (0.38) | MAPTPKM | |
| SCHEMBL1426485 | 0.67 | LMNA (0.41) | KDM4EALDH1A1MEN1MAPTPKM | |
| SCHEMBL7796649 | 0.66 | MAPT (0.38) | GAAKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL20607282 | 0.66 | SMN1; SMN2 (0.41) | GAAKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL20614632 | 0.65 | ALDH1A1 (0.37) | ALDH1A1MEN1PKMKMT2A | |
| SCHEMBL6327634 | 0.64 | PTGS1 (0.42) | KDM4EALDH1A1MEN1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123548-A | (2-Oxo-pyrrolidines)-acetic hydrazides | CHEMISCHES LABORATORIUM FRITZ-WALTER LANGE GMBH & CO KG (DE) | 1978-10-31 | — | — | US | disclosed |
| US-4069336-A | PSYCHOPHARMACONS, NOOTROPIC AGENTS | CHEMISCHES LABORATORIUM FRITZ-WALTER LANGE GMBH & CO KG (DT) | 1978-01-17 | — | — | US | disclosed |