Lanceolatin B

Lanceolatin B

SCHEMBL1161113

O=c1cc(-c2ccccc2)oc2c1ccc1occc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1B1 Q16678 10/20 1.00
▸ CYP1A1 P04798 8/20 1.00
▸ CYP1A2 P05177 6/20 1.00
▸ CCNT1 O60563 1/20 0.74
▸ CDK7 P50613 1/20 0.74
▸ CDK9 P50750 1/20 0.74
▸ CCNH P51946 1/20 0.74
▸ MNAT1 P51948 1/20 0.74
▸ CYP19A1 P11511 5/20 0.62
▸ CYP3A4 P08684 5/20 0.62
▸ HPGD P15428 5/20 0.62
▸ MAPT P10636 5/20 0.62
▸ TP53 P04637 4/20 0.62
▸ KDM4E B2RXH2 4/20 0.62
▸ ALDH1A1 P00352 4/20 0.62
▸ HSD17B10 Q99714 4/20 0.62
▸ MAPK1 P28482 3/20 0.62
▸ ABCB1 P08183 3/20 0.62
▸ ABCG2 Q9UNQ0 2/20 0.62
▸ CYP2D6 P10635 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21828763 0.82 CYP1A1 (0.69) CYP1B1CYP1A1CYP1A2CCNT1CDK7
SCHEMBL29598726 0.78 CYP1A1 (0.67) CYP1B1CYP1A1CYP1A2CCNT1CDK7
Pongaglabrone SCHEMBL29597920 0.78 CYP1A1 (1.00) CYP1B1CYP1A1CYP1A2CCNT1CDK7
Flavone SCHEMBL8613813 0.78 TNKS (0.79) CYP1B1CYP1A1CYP1A2CYP19A1CYP3A4
Alpha-Naphthoflavone SCHEMBL121594 0.77 CYP1A1 (1.00) CYP1B1CYP1A1CYP1A2CYP19A1CYP3A4
Alpha-Naphthoflavone SCHEMBL29351090 0.77 CYP1A1 (1.00) CYP1B1CYP1A1CYP1A2CYP19A1CYP3A4
SCHEMBL12279235 0.75 CYP1B1 (0.60) CYP1B1CYP1A1CYP1A2CCNT1CDK7
SCHEMBL5463385 0.75 CYP1A1 (0.67) CYP1B1CYP1A1CYP1A2CYP19A1CYP3A4
Alpha-Naphthoflavone SCHEMBL3665037 0.75 CYP1A1 (0.82) CYP1B1CYP1A1CYP1A2CYP19A1CYP3A4
SCHEMBL31632357 0.74 CYP1B1 (0.59) CYP1B1CYP1A1CYP1A2CYP19A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310281-A1 METHOD OF PROTECTING KERATIN MATERIALS FROM POLLUTANTS OREAL (FR) 2023-10-05 — — US disclosed
US-11771631-B2 Cosmetic composition comprising a specific filler combination and a film-forming polymer to increase long-lasting effects L'OREAL (FR) 2023-10-03 — — US disclosed
EP-2872106-B2 COMPOSITE PIGMENT AND METHOD FOR PREPARING THE SAME OREAL (FR) 2023-08-02 — — EP disclosed
US-11540539-B2 Reduced sodium food products GENERAL MILLS, INC. (US) 2023-01-03 — — US disclosed
US-11523976-B2 Composite pigment and method for preparing the same L'OREAL (FR) 2022-12-13 — — US disclosed
EP-3528782-B1 METHOD OF PROTECTING KERATIN MATERIALS FROM POLLUTANTS OREAL (FR) 2022-11-30 — — EP disclosed
EP-3466930-B1 REDUCED SODIUM FOOD PRODUCT GEN MILLS INC (US) 2022-07-20 — — EP disclosed
CN-108366924-B Cosmetic composition comprising a specific filler combination and a film-forming polymer to improve long-lasting effect 莱雅公司 2021-03-02 — — CN disclosed
US-20210007955-A1 COSMETIC COMPOSITION COMPRISING A SPECIFIC FILLER COMBINATION AND A FILM-FORMING POLYMER TO INCREASE LONG-LASTING EFFECTS L'OREAL (FR) 2021-01-14 — — US disclosed
US-20200281236-A1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2020-09-10 — — US disclosed
US-20130259912-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'OREAL (FR) 2013-10-03 — — US disclosed
WO-2012105723-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'OREAL (FR) 2012-08-09 — — WO disclosed
WO-2012105060-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'OREAL (FR) 2012-08-09 — — WO disclosed
WO-2012105059-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'OREAL (FR) 2012-08-09 — — WO disclosed
EP-2462199-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'Oréal (FR) 2012-06-13 — — EP disclosed
EP-2462197-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'Oréal (FR) 2012-06-13 — — EP disclosed
WO-2011016143-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'OREAL (FR) 2011-02-10 — — WO disclosed
WO-2011016139-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'OREAL (FR) 2011-02-10 — — WO disclosed
WO-2011016144-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'OREAL (FR) 2011-02-10 — — WO disclosed
WO-2011016140-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'OREAL (FR) 2011-02-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210007955-A1 COSMETIC COMPOSITION COMPRISING A SPECIFIC FILLER COMBINATION AND A FILM-FORMING POLYMER TO INCREASE LONG-LASTING EFFECTS CUTA, KRT18, PUF60 CYP1B1 3599/4885CYP1A1 2658/4885CYP1A2 2361/4885
US-20130259912-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF TYR, MITF, PUF60 CYP1B1 1863/4885CYP1A1 1791/4885CYP1A2 2746/4885
US-11523976-B2 Composite pigment and method for preparing the same INCENP, TYR, EXOSC9 CYP1B1 2713/4885CYP1A1 1779/4885CYP1A2 2197/4885
US-20230310281-A1 METHOD OF PROTECTING KERATIN MATERIALS FROM POLLUTANTS KRT18, DSG1, JUP CYP1B1 2518/4885CYP1A1 1832/4885CYP1A2 3124/4885
US-11771631-B2 Cosmetic composition comprising a specific filler combination and a film-forming polymer to increase long-lasting effects CUTA, KRT18, PUF60 CYP1B1 3599/4885CYP1A1 2658/4885CYP1A2 2361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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