Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MGAM | O43451 | 3/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.41 |
| ▸ | SI | P14410 | 3/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161528 | 0.84 | FAAH (0.40) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL18031569 | 0.82 | KCNMA1 (0.53) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL18031574 | 0.81 | ALDH1A1 (0.44) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL18031571 | 0.80 | KCNMA1 (0.54) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL31666989 | 0.77 | KCNMA1 (0.53) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL1161338 | 0.77 | KCNMA1 (0.53) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL10428733 | 0.77 | KCNMA1 (0.62) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL11440840 | 0.75 | KCNMA1 (0.61) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL4054573 | 0.75 | KCNMA1 (0.61) | KCNMA1GAAMGAMAMY1ASI | |
| SCHEMBL24019555 | 0.74 | KCNMA1 (0.59) | KCNMA1GAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012622-A1 | BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF GLYTL MEDIATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2011-02-03 | — | — | WO | disclosed |