Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10547068 | 0.88 | HNF4A (0.50) | GPR35POLBDHODHNPC1KMT2A | |
| SCHEMBL11621112 | 0.82 | PSMD14 (0.56) | GPR35POLBNPC1RAB9AKMT2A | |
| SCHEMBL11554183 | 0.79 | POLB (0.51) | POLBNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL11621083 | 0.79 | MCL1 (0.46) | DHODHKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31491647 | 0.78 | ALB (0.47) | GPR35DHODHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8876175 | 0.78 | ALOX15 (0.58) | POLBDHODHNPC1RAB9AKMT2A | |
| SCHEMBL11619785 | 0.77 | ALOX15 (0.51) | DHODHNPC1RAB9AALDH1A1BCL2L1 | |
| SCHEMBL11702360 | 0.77 | SMN1; SMN2 (0.41) | SLC6A4SLC6A3POLBNPC1RAB9A | |
| SCHEMBL11621890 | 0.77 | GPR35 (0.41) | GPR35POLBDHODHNPC1RAB9A | |
| SCHEMBL11704909 | 0.75 | GSK3B (0.40) | POLBNPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124603-A | ANTIMICROBIAL | RIKER LABORATORIES, INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4067993-A | Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids | RIKER LABORATORIES, INC. (US) | 1978-01-10 | — | — | US | disclosed |