Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | BAD | Q92934 | 2/20 | 0.44 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABL2 | P42684 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10547068 | 0.85 | HNF4A (0.50) | ALOX15ALOX12NPC1L3MBTL1PSMD14 | |
| SCHEMBL11621083 | 0.80 | MCL1 (0.46) | MCL1PSMD14ALDH1A1TP53DHODH | |
| SCHEMBL13990447 | 0.77 | DCLRE1B (0.44) | ALOX15ALOX12PIK3CAMCL1BAD | |
| SCHEMBL11623441 | 0.77 | GPR35 (0.44) | BADCA12CA9NPC1RAB9A | |
| SCHEMBL11704945 | 0.77 | ALOX15 (0.49) | ALOX15ALOX12PIK3CAEGFRABL1 | |
| SCHEMBL269867 | 0.76 | HNF4A (0.53) | MCL1BADDCLRE1BNPC1RAB9A | |
| SCHEMBL8876175 | 0.75 | ALOX15 (0.58) | ALOX15ALOX12PIK3CANPC1RAB9A | |
| SCHEMBL11621112 | 0.74 | PSMD14 (0.56) | NPC1RAB9APSMD14ALDH1A1TP53 | |
| SCHEMBL10983495 | 0.73 | CYP1A1 (0.63) | — | |
| SCHEMBL121632 | 0.72 | DHODH (0.70) | DCLRE1BNPC1RAB9AL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124603-A | ANTIMICROBIAL | RIKER LABORATORIES, INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4067993-A | Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids | RIKER LABORATORIES, INC. (US) | 1978-01-10 | — | — | US | disclosed |