Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11630996 | 1.00 | SIGMAR1 (0.46) | SIGMAR1DRD2L3MBTL1HTR7CCR3 | |
| SCHEMBL11629536 | 0.99 | SIGMAR1 (0.46) | SIGMAR1DRD2L3MBTL1HTR7CCR3 | |
| SCHEMBL11634992 | 0.93 | L3MBTL1 (0.53) | SIGMAR1DRD2L3MBTL1HTR7OPRL1 | |
| SCHEMBL11634977 | 0.84 | L3MBTL1 (0.47) | DRD2L3MBTL1CCR3OPRL1CCR1 | |
| SCHEMBL11804225 | 0.82 | DRD2 (0.57) | SIGMAR1DRD2HTR7HTR1AHTR2A | |
| SCHEMBL11807499 | 0.82 | DRD2 (0.57) | SIGMAR1DRD2HTR7HTR1AHTR2A | |
| SCHEMBL11631445 | 0.82 | SIGMAR1 (0.47) | SIGMAR1L3MBTL1HTR7MEN1KMT2A | |
| SCHEMBL11629868 | 0.82 | SIGMAR1 (0.47) | SIGMAR1L3MBTL1HTR7MEN1KMT2A | |
| SCHEMBL11630627 | 0.82 | HTR7 (0.61) | DRD2L3MBTL1HTR7HTR1AHTR2A | |
| SCHEMBL11633969 | 0.82 | L3MBTL1 (0.47) | DRD2L3MBTL1MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |