Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631639 | 0.91 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL11631327 | 0.81 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL11631833 | 0.80 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL11631928 | 0.80 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL11805397 | 0.79 | DRD2 (0.48) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL11632587 | 0.77 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL11629224 | 0.77 | DRD2 (0.56) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL11629904 | 0.77 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL11629801 | 0.75 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL11634977 | 0.75 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |