Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.60 |
| ▸ | DRD2 | P14416 | 4/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | HTR6 | P50406 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | DRD1 | P21728 | 3/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632263 | 0.94 | HTR7 (0.64) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL11629816 | 0.94 | HTR7 (0.67) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL11631804 | 0.85 | L3MBTL1 (0.59) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL11628968 | 0.82 | DRD2 (0.58) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL11629077 | 0.81 | L3MBTL1 (0.56) | KDM4ESMN1; SMN2L3MBTL1MAPTADRA1D | |
| SCHEMBL11635081 | 0.81 | L3MBTL1 (0.56) | L3MBTL1MAPTADRA1DADRA1AADRA1B | |
| SCHEMBL11629224 | 0.80 | DRD2 (0.56) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL11632645 | 0.80 | L3MBTL1 (0.50) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL11630691 | 0.80 | KDM4E (0.61) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL11633831 | 0.80 | HTR1A (0.85) | HTR7DRD2HTR1AHTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |