Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 6/20 | 0.48 |
| ▸ | HTR1A | P08908 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 6/20 | 0.48 |
| ▸ | HTR2A | P28223 | 6/20 | 0.48 |
| ▸ | HTR6 | P50406 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11629224 | 0.92 | DRD2 (0.56) | L3MBTL1HTR7HTR1ADRD2HTR2A | |
| SCHEMBL11631804 | 0.88 | L3MBTL1 (0.59) | L3MBTL1HTR7HTR1ADRD2HTR2A | |
| SCHEMBL11630691 | 0.85 | KDM4E (0.61) | L3MBTL1HTR7HTR1ADRD2HTR2A | |
| SCHEMBL11628968 | 0.85 | DRD2 (0.58) | L3MBTL1HTR7HTR1ADRD2HTR2A | |
| SCHEMBL11630154 | 0.84 | HTR1A (0.47) | L3MBTL1HTR7HTR1ADRD2HTR2A | |
| SCHEMBL11629079 | 0.84 | L3MBTL1 (0.51) | L3MBTL1HTR7HTR1ADRD2HTR2A | |
| SCHEMBL11632587 | 0.83 | L3MBTL1 (0.50) | L3MBTL1HTR7HTR1ADRD2HTR2A | |
| SCHEMBL11635491 | 0.83 | HTR7 (0.59) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL11631256 | 0.83 | HTR1A (0.62) | L3MBTL1HTR7HTR1ADRD2HTR2A | |
| SCHEMBL11630627 | 0.82 | HTR7 (0.61) | L3MBTL1HTR7HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |