Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 11/20 | 0.42 |
| ▸ | HTR7 | P34969 | 10/20 | 0.42 |
| ▸ | HTR1A | P08908 | 9/20 | 0.42 |
| ▸ | HTR2A | P28223 | 9/20 | 0.42 |
| ▸ | HTR6 | P50406 | 9/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628968 | 0.83 | DRD2 (0.58) | L3MBTL1DRD2HTR7HTR1AHTR2A | |
| SCHEMBL11636284 | 0.81 | DRD2 (0.63) | DRD2HTR7HTR1AHTR2AHTR6 | |
| SCHEMBL11631804 | 0.80 | L3MBTL1 (0.59) | L3MBTL1DRD2HTR7HTR1AHTR2A | |
| SCHEMBL11634432 | 0.79 | L3MBTL1 (0.44) | L3MBTL1DRD2HTR7HTR1AHTR2A | |
| SCHEMBL11629079 | 0.78 | L3MBTL1 (0.51) | L3MBTL1DRD2HTR7HTR1AHTR2A | |
| SCHEMBL11632015 | 0.76 | HTR7 (0.60) | L3MBTL1DRD2HTR7HTR1AHTR2A | |
| SCHEMBL11629077 | 0.76 | L3MBTL1 (0.56) | L3MBTL1KDM4E | |
| SCHEMBL11635081 | 0.76 | L3MBTL1 (0.56) | L3MBTL1 | |
| SCHEMBL11630691 | 0.75 | KDM4E (0.61) | L3MBTL1DRD2HTR7HTR1AHTR2A | |
| SCHEMBL11629224 | 0.75 | DRD2 (0.56) | L3MBTL1DRD2HTR7HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |