Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 3/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65330 | 0.88 | CTRC (0.36) | CTRCNOTUMRAB9APTGESMEN1 | |
| SCHEMBL11661835 | 0.82 | ALDH1A1 (0.36) | CTRCRAB9AMEN1KMT2AKDM4E | |
| Thianthrene SCHEMBL8580618 | 0.78 | PSMB8 (0.32) | CTRCPSMB8 | |
| SCHEMBL8986271 | 0.77 | ALDH1A1 (0.47) | CTRCNOTUMRAB9AKMT2AKDM4E | |
| SCHEMBL11659237 | 0.70 | P2RX7 (0.43) | RAB9AKMT2AALDH1A1MAPTLMNA | |
| SCHEMBL9351602 | 0.70 | ALDH1A1 (0.40) | CTRCRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11661914 | 0.70 | PDE4B (0.43) | PDGFRAMAPK8CDK5CLK4CTRC | |
| SCHEMBL6308790 | 0.69 | GPR3 (0.39) | RAB9AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3627652 | 0.66 | BCL2L1 (0.42) | RAB9AMEN1KMT2AALDH1A1MAPT | |
| Biphenyl SCHEMBL28878184 | 0.59 | ALDH1A1 (0.53) | CTRCNOTUMALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122090-A | Cyclic esters of 3,4-dihydroxy-thiophene-1,1-dioxide compounds and 3,4-dihydroxy-cyclopentadienone compounds | BASF AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |