SCHEMBL65330

SCHEMBL65330

O=c1oc2c(o1)=C(c1ccccc1)S(=O)(=O)C=2c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 3/20 0.36
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
CA12 O43570 2/20 0.33
CA9 Q16790 2/20 0.33
PSMB8 P28062 2/20 0.33
NOTUM Q6P988 1/20 0.33
RAB9A P51151 3/20 0.32
NPC1 O15118 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
ALDH1A1 P00352 3/20 0.32
KMT2A Q03164 2/20 0.32
HPGD P15428 2/20 0.32
KDM4E B2RXH2 2/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
TNKS O95271 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thianthrene SCHEMBL8580618 0.89 PSMB8 (0.32) CTRCPSMB8
SCHEMBL11656759 0.88 PDGFRA (0.38) CTRCLMNAMAPTHTTCA12
SCHEMBL11661835 0.82 ALDH1A1 (0.36) CTRCMAPTRAB9ANPC1SMN1; SMN2
SCHEMBL8986271 0.77 ALDH1A1 (0.47) CTRCLMNAMAPTHTTCA12
SCHEMBL11659237 0.70 P2RX7 (0.43) LMNAMAPTHTTCA12CA9
SCHEMBL9351602 0.70 ALDH1A1 (0.40) CTRCLMNAMAPTHTTCA12
SCHEMBL11665419 0.70 PDE4B (0.43) CTRCLMNAMAPTHTTPSMB8
SCHEMBL6308790 0.69 GPR3 (0.39) LMNAMAPTHTTCA12CA9
SCHEMBL48083 0.67 KDM4E (0.44) CTRCLMNAMAPTHTTCA12
SCHEMBL3627652 0.66 BCL2L1 (0.42) LMNAMAPTHTTCA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5856299-A ESTERIFICATION WITH ALCOHOL FIDIA ADVANCED BIOPOLYMERS S.R.L. (IT) 1999-01-05 US claimed
US-5753412-A Photoresist having increased sensitivity and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-05-19 US claimed
US-5593812-A Photoresist having increased sensitivity and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-01-14 US claimed
EP-0727713-A1 Photoresist having increased sensitivity and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-08-21 EP claimed
US-4122090-A Cyclic esters of 3,4-dihydroxy-thiophene-1,1-dioxide compounds and 3,4-dihydroxy-cyclopentadienone compounds BASF AKTIENGESELLSCHAFT (DE) 1978-10-24 US claimed
JP-8254822-A None JP disclosed
EP-2149586-B1 AMINE EPOXY RESIN CURING AGENT, GAS BARRIER EPOXY RESIN COMPOSITION COMPRISING THE CURING AGENT, COATING AGENT, AND ADHESIVE AGENT FOR LAMINATE MITSUBISHI GAS CHEMICAL CO (JP) 2018-01-03 EP disclosed
US-8128782-B2 Amine epoxy resin curing agent, gas barrier epoxy resin composition comprising the curing agent, coating agent, and adhesive agent for laminate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-03-06 US disclosed
US-20100160494-A1 AMINE EPOXY RESIN CURING AGENT, GAS BARRIER EPOXY RESIN COMPOSITION COMPRISING THE CURING AGENT, COATING AGENT, AND ADHESIVE AGENT FOR LAMINATE MITSUBISHI GAS CHEMICAL COMPANY INC. (JP) 2010-06-24 US disclosed
EP-2149586-A1 AMINE EPOXY RESIN CURING AGENT, GAS BARRIER EPOXY RESIN COMPOSITION COMPRISING THE CURING AGENT, COATING AGENT, AND ADHESIVE AGENT FOR LAMINATE Mitsubishi Gas Chemical Company, Inc. (JP) 2010-02-03 EP disclosed
EP-0749446-B1 HIGHLY REACTIVE ESTERS OF CARBOXY POLYSACCHARIDES AND NOVEL CARBOXY POLYSACCHARIDES DERIVED THEREFROM FIDIA ADVANCED BIOPOLYMERS SRL (IT) 1999-11-24 EP disclosed
US-5770345-A Photoresist having increased sensitivity and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-06-23 US disclosed
US-5352551-A Process for storing information with high storage density CIBA-GEIGY CORPORATION (US) 1994-10-04 US disclosed
US-5116835-A Hypotensive agents HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed
US-4595733-A Aromatic polycarbonate containing thieno-2-one-5,5-dioxide terminal groups GENERAL ELECTRIC COMPANY (US) 1986-06-17 US disclosed
EP-0177792-A1 Hydrolytically stabilized polycarbonates GENERAL ELECTRIC COMPANY (US) 1986-04-16 EP disclosed
US-4576982-A Hydrolytically stabilized polycarbonates GENERAL MOTORS COMPANY (US) 1986-03-18 US disclosed
US-4438260-A Sisomicin compounds BAYER AKTIENGESELLSCHAFT (DE) 1984-03-20 US disclosed
US-4234572-A AMINOGLYCOSIDE ANTIBIOTICS BAYER AKTIENGESELLSCHAFT (DE) 1980-11-18 US disclosed
US-4122090-A Cyclic esters of 3,4-dihydroxy-thiophene-1,1-dioxide compounds and 3,4-dihydroxy-cyclopentadienone compounds BASF AKTIENGESELLSCHAFT (DE) 1978-10-24 US disclosed