Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679519 | 0.92 | MAPT (0.49) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL11679201 | 0.82 | RAB9A (0.51) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL11675968 | 0.76 | L3MBTL1 (0.58) | MAPTRAB9ANPC1KMT2AKDM4E | |
| SCHEMBL11869257 | 0.76 | PTGS2 (0.36) | MAPTRAB9ANPC1HSD17B1KDM4E | |
| SCHEMBL11800787 | 0.76 | ABCC4 (0.35) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11677514 | 0.72 | MAPT (0.53) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL11679626 | 0.70 | MAPT (0.58) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL11678574 | 0.70 | KDM4E (0.54) | MAPTRAB9ANPC1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL31070035 | 0.70 | MAPT (0.50) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL11552117 | 0.70 | TTR (0.38) | RAB9ANPC1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |