Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11697243 | 0.83 | ALDH1A1 (0.49) | KDM4EPOLBPLA2G4BALDH1A1LMNA | |
| SCHEMBL11295734 | 0.80 | PLA2G4B (0.51) | KDM4EPOLBPLA2G4BALDH1A1LMNA | |
| SCHEMBL503308 | 0.79 | PLA2G4B (0.58) | POLBPLA2G4BALDH1A1CA2CAMK2A | |
| SCHEMBL11683055 | 0.79 | PLA2G4B (0.61) | KDM4EPLA2G4BALDH1A1LMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL2528810 | 0.78 | PLA2G4B (0.56) | KDM4EPOLBPLA2G4BALDH1A1SMN1; SMN2 | |
| SCHEMBL14516116 | 0.78 | PKM (0.56) | POLBPLA2G4BCA2SMN1; SMN2ALOX15 | |
| Dimethylamine SCHEMBL1630099 | 0.78 | KDM4E (0.73) | KDM4EPOLBALDH1A1LMNAPTGS1 | |
| SCHEMBL5224516 | 0.77 | PLA2G4B (0.56) | KDM4EPOLBPLA2G4BALDH1A1LMNA | |
| SCHEMBL11684213 | 0.77 | PLA2G4B (0.69) | KDM4EPLA2G4BALDH1A1LMNACA2 | |
| SCHEMBL9832704 | 0.77 | ALOX15 (0.63) | PLA2G4BALDH1A1CA2CAMK2ASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243547-A1 | LINEAR (PER) FLUOROPOLYETHERS WITH -CF(CF3)COF END GROUPS AND DERIVATIVES THEREOF | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2014-08-28 | — | — | US | disclosed |
| US-20140243547-A1 | LINEAR (PER) FLUOROPOLYETHERS WITH -CF(CF3)COF END GROUPS AND DERIVATIVES THEREOF | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2014-08-28 | — | — | US | disclosed |
| WO-2013050273-A1 | LINEAR (PER)FLUOROPOLYETHERS WITH -CF(CF3)COF END GROUPS AND DERIVATIVES THEREOF | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243547-A1 | LINEAR (PER) FLUOROPOLYETHERS WITH -CF(CF3)COF END GROUPS AND DERIVATIVES THEREOF | COXFA4, CYP4F3, ETFB | KDM4E 3068/4885POLB 157/4885PLA2G4B 2785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.