Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.63 |
| ▸ | DRD3 | P35462 | 10/20 | 0.63 |
| ▸ | DRD2 | P14416 | 9/20 | 0.63 |
| ▸ | DRD4 | P21917 | 7/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.63 |
| ▸ | HTR1A | P08908 | 3/20 | 0.63 |
| ▸ | SCN1A | P35498 | 3/20 | 0.63 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.63 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836914 | 0.85 | OPRM1 (0.69) | OPRM1DRD3DRD2DRD4CYP2D6 | |
| SCHEMBL2221753 | 0.85 | OPRM1 (0.71) | OPRM1DRD3DRD2DRD4CYP2D6 | |
| Norpipanone SCHEMBL25085 | 0.83 | OPRM1 (0.75) | OPRM1DRD3DRD2CYP2D6CHRM2 | |
| Norpipanone SCHEMBL316886 | 0.82 | OPRM1 (0.73) | OPRM1DRD3DRD2CYP2D6CHRM2 | |
| SCHEMBL6841125 | 0.81 | OPRM1 (0.73) | OPRM1DRD3DRD2DRD4CYP2D6 | |
| Fenpipramide SCHEMBL149504 | 0.81 | CHRM2 (0.60) | OPRM1DRD3DRD2CYP2D6CHRM2 | |
| SCHEMBL219257 | 0.81 | CHRM2 (0.60) | OPRM1DRD3DRD2CYP2D6CHRM2 | |
| SCHEMBL10575924 | 0.81 | CYP2D6 (0.50) | OPRM1DRD3DRD2DRD4CYP2D6 | |
| SCHEMBL10768406 | 0.81 | OPRM1 (0.63) | OPRM1DRD3DRD2DRD4CYP2D6 | |
| Fenpipramide SCHEMBL11716116 | 0.81 | OPRM1 (0.56) | OPRM1DRD3DRD2CYP2D6CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160311788-A1 | Antifouling Compounds And Use Thereof | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-10-27 | — | — | US | disclosed |
| US-20160311788-A1 | Antifouling Compounds And Use Thereof | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-10-27 | — | — | US | disclosed |
| US-20160311788-A1 | Antifouling Compounds And Use Thereof | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-10-27 | — | — | US | disclosed |
| EP-2294144-B1 | ANTIFOULING COMPOUNDS AND USE THEREOF | UNIV SINGAPORE (SG) | 2014-03-05 | — | — | EP | disclosed |
| EP-2294144-B1 | ANTIFOULING COMPOUNDS AND USE THEREOF | UNIV SINGAPORE (SG) | 2014-03-05 | — | — | EP | disclosed |
| US-20110092518-A1 | Antifouling Compounds And Use Thereof | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2011-04-21 | — | — | US | disclosed |
| US-20110092518-A1 | Antifouling Compounds And Use Thereof | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2011-04-21 | — | — | US | disclosed |
| US-20110092518-A1 | Antifouling Compounds And Use Thereof | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2011-04-21 | — | — | US | disclosed |
| EP-2294144-A1 | ANTIFOULING COMPOUNDS AND USE THEREOF | National University of Singapore (SG) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009139729-A1 | ANTIFOULING COMPOUNDS AND USE THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2009-11-19 | — | — | WO | disclosed |
| WO-2009139729-A1 | ANTIFOULING COMPOUNDS AND USE THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2009-11-19 | — | — | WO | disclosed |
| EP-1058684-A1 | GLYCINE TRANSPORT INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-12-13 | — | — | EP | disclosed |
| WO-1999045011-A1 | GLYCINE TRANSPORT INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-09-10 | — | — | WO | disclosed |
| EP-0219898-A1 | Novel alpha,alpha-diaryl-4-aryl-4-hydroxy-1-piperidinebutanamide, N-oxides | JANSSEN PHARMACEUTICA N.V. (BE) | 1987-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311788-A1 | Antifouling Compounds And Use Thereof | C5, C9, C1S | OPRM1 355/4885DRD3 945/4885DRD2 807/4885 |
| US-20110092518-A1 | Antifouling Compounds And Use Thereof | C5, C9, C1S | OPRM1 362/4885DRD3 944/4885DRD2 807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.