SCHEMBL11722467

SCHEMBL11722467

COC(=O)NS(=O)(=O)Cc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.54
MAPT P10636 2/20 0.54
JMJD7 P0C870 1/20 0.52
POLB P06746 3/20 0.48
HTT P42858 2/20 0.48
KMT2A Q03164 1/20 0.45
MAOB P27338 1/20 0.45
ALDH1A1 P00352 2/20 0.44
F2 P00734 1/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
RAB9A P51151 1/20 0.43
PTGS2 P35354 1/20 0.43
RORC P51449 1/20 0.43
PKM P14618 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815588 0.78 CA2 (0.59) GAAPOLBKMT2AALDH1A1F2
SCHEMBL3001018 0.78 CA1 (0.58) GAAMAPTPOLBHTTKMT2A
SCHEMBL9303069 0.77 POLB (0.48) GAAMAPTPOLBHTTKMT2A
SCHEMBL8896563 0.77 MAPT (0.50) GAAMAPTJMJD7HTTKMT2A
SCHEMBL10494766 0.76 MAPT (0.53) GAAMAPTJMJD7HTTKMT2A
SCHEMBL6769979 0.76 MMP13 (0.48) GAAMAPTJMJD7POLBHTT
SCHEMBL6589048 0.76 MMP13 (0.48) GAAMAPTJMJD7POLBHTT
SCHEMBL21596169 0.76 LOXL2 (0.55) GAAMAPTHTTKMT2ACA12
SCHEMBL28498471 0.76 HTT (0.57) POLBHTTKMT2AALDH1A1CA12
SCHEMBL18040277 0.76 RAB9A (0.59) GAAPOLBHTTMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4029687-A HERBICIDES CIBA-GEIGY AG (CH) 1977-06-14 US disclosed
US-4004914-A HERBICIDES CIBA-GEIGY AG (CH) 1977-01-25 US disclosed
US-3951641-A Use of N-(4-isopropoxy-3-chlorophenyl)-N'-methyl-N'-methoxyurea for control of weeds in maize cultures CIBA-GEIGY AG (CH) 1976-04-20 US disclosed