Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11848646 | 0.89 | MAPT (0.43) | TDP1HPGDALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11728716 | 0.89 | ALDH1A1 (0.40) | ALDH1A1NAMPTPPARG | |
| SCHEMBL11733330 | 0.88 | CYP1A2 (0.47) | CYP1A2GAACYP2C19TDP1HPGD | |
| SCHEMBL11730754 | 0.87 | LTA4H (0.45) | ALDH1A1NAMPT | |
| SCHEMBL11732372 | 0.86 | FAAH (0.36) | — | |
| SCHEMBL11730159 | 0.85 | TBXA2R (0.45) | GAAALDH1A1 | |
| SCHEMBL11726046 | 0.83 | FAAH (0.40) | — | |
| SCHEMBL11852592 | 0.82 | ALDH1A1 (0.42) | GAAALDH1A1 | |
| SCHEMBL11730971 | 0.82 | ADRB2 (0.43) | HPGDSMN1; SMN2 | |
| SCHEMBL11728722 | 0.81 | TBXAS1 (0.42) | TDP1HPGDALDH1A1NAMPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |