SCHEMBL1173377

SCHEMBL1173377

OCC=CCC1=CCCC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11657679 0.94 ALDH1A1 (0.39) ALOX15ALDH1A1TAAR1SMN1; SMN2
SCHEMBL9384271 0.94 ALDH1A1 (0.39) ALOX15ALDH1A1TAAR1SMN1; SMN2
SCHEMBL4018505 0.81
SCHEMBL3946326 0.79 ALOX15 (0.36) ALOX15ALDH1A1SMN1; SMN2
SCHEMBL9848964 0.79 ALOX15 (0.36) ALOX15ALDH1A1SMN1; SMN2
SCHEMBL2301191 0.79 ALOX15 (0.36) ALOX15ALDH1A1SMN1; SMN2
SCHEMBL18754403 0.77
SCHEMBL8083435 0.77
SCHEMBL6159550 0.77
SCHEMBL3946063 0.76 ALDH1A1 (0.34) ALOX15ALDH1A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1256336-B1 Two-phase gel composition PENRECO (US) 2016-10-19 EP disclosed
US-9339446-B2 Gel composition CALUMET PENRECO, LLC (US) 2016-05-17 US disclosed
US-8771718-B2 Formulated tick and insect repellent compositions E I DU PONT DE NEMOURS AND COMPANY (US) 2014-07-08 US disclosed
EP-2094650-B1 USE OF CAMPHOLENIC DERIVATIVES AS FRAGRANT INGREDIENTS IN PERFUMERY AND FLAVOURING MANE FILS V (FR) 2011-09-21 EP disclosed
EP-2337544-A2 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE Living Proof, Inc. (US) 2011-06-29 EP disclosed
US-20110045983-A1 Gel composition WILMINGTON TRUST, NATIONAL ASSOCIATION 2011-02-24 US disclosed
US-20090232753-A1 Gel compositions HEALY LIN LU 2009-09-17 US disclosed
EP-2094650-A1 USE OF CAMPHOLENIC DERIVATIVES AS FRAGRANT INGREDIENTS IN PERFUMERY AND FLAVOURING V. Mane Fils (FR) 2009-09-02 EP disclosed
EP-2040555-A2 FORMULATED TICK AND INSECT REPELLENT COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-04-01 EP disclosed
US-20090068255-A1 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE LIVING PROOF, INC. 2009-03-12 US disclosed
WO-2007133683-A2 FORMULATED TICK AND INSECT REPELLENT COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-22 WO disclosed
US-20070264297-A1 Formulated tick and insect repellent compositions 1,4Group, Inc. 2007-11-15 US disclosed
EP-1141111-B1 GEL COMPOSITIONS PENRECO (US) 2005-08-03 EP disclosed
US-6881776-B2 Gel compositions PENRECO (US) 2005-04-19 US disclosed
US-20050004274-A1 Gel compositions HEALY LIN LU (US) 2005-01-06 US disclosed
EP-1256336-A2 Two-phase gel composition Penreco (US) 2002-11-13 EP disclosed
US-20020055562-A1 Gel compositions WILMINGTON TRUST, NATIONAL ASSOCIATION 2002-05-09 US disclosed
EP-0838451-B1 PROCESS FOR PRODUCING UNSATURATED ALCOHOLS KAO CORP (JP) 2001-11-28 EP disclosed
EP-1141111-A1 GEL COMPOSITIONS Penreco (US) 2001-10-10 EP disclosed
WO-2000026285-A1 GEL COMPOSITIONS PENRECO (US) 2000-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068255-A1 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE MMP1, MMP9, MMP17 ALOX15 798/4885ALDH1A1 2338/4885TAAR1 3058/4885
US-20110045983-A1 Gel composition PGR, COPE, PTGER1 ALOX15 757/4885ALDH1A1 3560/4885TAAR1 1036/4885
US-20070264297-A1 Formulated tick and insect repellent compositions MME, FNTA, ACHE ALOX15 3460/4885ALDH1A1 3113/4885TAAR1 556/4885
US-20090232753-A1 Gel compositions PGR, COPE, PTGER1 ALOX15 791/4885ALDH1A1 3505/4885TAAR1 998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.