Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 5/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315411 | 0.82 | PARP1 (0.46) | CES2CES1PARP1GPBAR1PIK3CA | |
| SCHEMBL15088204 | 0.81 | ALDH1A1 (0.53) | BTKPLCG1JAK3 | |
| SCHEMBL19890630 | 0.81 | HSD17B1 (0.51) | BTKJAK3 | |
| SCHEMBL23531983 | 0.81 | BTK (0.41) | BTKPLCG1JAK3 | |
| SCHEMBL29989323 | 0.80 | BTK (0.46) | BTKPLCG1JAK3 | |
| SCHEMBL7779064 | 0.80 | HTR3E (0.54) | BTKGPBAR1 | |
| SCHEMBL15974825 | 0.80 | BTK (0.46) | BTKPLCG1JAK3 | |
| SCHEMBL7535315 | 0.80 | EGFR (0.50) | BTKCES2 | |
| SCHEMBL10194673 | 0.79 | BCL2A1 (0.49) | BRD4 | |
| SCHEMBL2089023 | 0.79 | CES2 (0.44) | CES2CES1PARP1GPBAR1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048018-A | Method of carrying out enzyme catalyzed reactions | COUGHLIN ROBERT W | 1977-09-13 | — | — | US | disclosed |
| US-4016293-A | ADSORBED ON A SUPPORT, CHEESE WHEY | COUGHLIN ROBERT W | 1977-04-05 | — | — | US | disclosed |