Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11758570 | 0.91 | MAOA (0.35) | IDO1MAOBMAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL10728607 | 0.82 | TSHR (0.35) | IDO1MAOBMAOAALDH1A1SIGMAR1 | |
| SCHEMBL338864 | 0.78 | SIGMAR1 (0.37) | MAOAPOLBSIGMAR1TAAR1OPRM1 | |
| SCHEMBL16243044 | 0.77 | OPRM1 (0.37) | MAOBMAOAPOLBSIGMAR1OPRM1 | |
| SCHEMBL477537 | 0.74 | KDM1A (0.35) | MAOBMAOAALDH1A1OPRM1 | |
| SCHEMBL2362597 | 0.73 | — | — | |
| SCHEMBL29211961 | 0.73 | — | — | |
| SCHEMBL2362254 | 0.73 | — | — | |
| SCHEMBL31288 | 0.73 | SCN2A (0.31) | ALDH1A1 | |
| SCHEMBL24045730 | 0.72 | DHFR (0.39) | IDO1MAOBMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119757-B2 | Polysiloxane and urethane modified water-reducible alkyd resins | CYTEC SURFACE SPECIALTIES AUSTRIA GMBH (AT) | 2012-02-21 | — | — | US | disclosed |