SCHEMBL1176779

SCHEMBL1176779

CC(C)(C)C(=O)c1ccc(N[C]=O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
PGR P06401 1/20 0.40
AR P10275 1/20 0.40
MLYCD O95822 2/20 0.38
NPC1 O15118 4/20 0.37
RAB9A P51151 4/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 4/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
GAA P10253 2/20 0.36
MITF O75030 1/20 0.36
HPGD P15428 1/20 0.36
CA2 P00918 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29196079 0.79 MAPK13 (0.47) L3MBTL1PGRARMLYCDNPC1
SCHEMBL10031827 0.78 PGR (0.47) L3MBTL1PGRARMLYCDLMNA
SCHEMBL1176735 0.78 LMNA (0.45) NPC1RAB9ALMNAMAPTKMT2A
SCHEMBL8284442 0.78 L3MBTL1 (0.45) L3MBTL1PGRARMLYCDNPC1
SCHEMBL5640360 0.78 MAPT (0.50) L3MBTL1NPC1RAB9ALMNAMAPT
SCHEMBL1176999 0.77 L3MBTL1 (0.73) L3MBTL1NPC1RAB9ALMNAMAPT
SCHEMBL10001145 0.76 L3MBTL1 (0.43) L3MBTL1PGRARMLYCDNPC1
SCHEMBL10079948 0.76 L3MBTL1 (0.43) L3MBTL1PGRARMLYCDNPC1
SCHEMBL1086164 0.75 TSHR (0.55) MEN1KMT2ASMN1; SMN2MITFCA2
SCHEMBL1701967 0.74 CA2 (0.57) NPC1RAB9ALMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110045397-A1 CHARGE CONTROL AGENT AND RELATED ART KURODA KAZUYOSHI 2011-02-24 US disclosed
US-20090053641-A1 CHARGE CONTROL AGENT AND RELATED ART ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2009-02-26 US disclosed
EP-1862860-A1 CHARGE CONTROL AGENT AND RELATED TECHNIQUE Orient Chemical Industries, Ltd. (JP) 2007-12-05 EP disclosed
CN-101044436-A Charge control agent and related technique ORIENT CHEMICAL IND (JP) 2007-09-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090053641-A1 CHARGE CONTROL AGENT AND RELATED ART H1-4, CECR2, DOT1L L3MBTL1 1185/4885PGR 2145/4885AR 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.