Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CES2 | O00748 | 3/20 | 0.56 |
| ▸ | CES1 | P23141 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18437044 | 0.93 | ALDH1A1 (0.70) | CA2ALDH1A1CES2CES1LMNA | |
| SCHEMBL13246736 | 0.93 | CA2 (0.52) | CA2ALDH1A1CES2CES1LMNA | |
| SCHEMBL10031827 | 0.89 | PGR (0.47) | CA2ALDH1A1CES2CES1LMNA | |
| SCHEMBL11528364 | 0.88 | MMP13 (0.58) | CA2ALDH1A1CES2CES1LMNA | |
| SCHEMBL9181194 | 0.83 | RAB9A (0.76) | ALDH1A1LMNASMN1; SMN2KMT2APKM | |
| SCHEMBL14588237 | 0.83 | CA2 (0.55) | CA2ALDH1A1CES2CES1LMNA | |
| SCHEMBL727083 | 0.83 | CA2 (0.55) | CA2ALDH1A1CES2CES1LMNA | |
| SCHEMBL9250001 | 0.83 | CA2 (0.55) | CA2ALDH1A1CES2CES1LMNA | |
| SCHEMBL195231 | 0.83 | CA2 (0.61) | CA2ALDH1A1CES2CES1LMNA | |
| SCHEMBL10483771 | 0.82 | ELANE (0.54) | ALDH1A1LMNAPKMHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362651-B1 | PROCESS FOR THE PRODUCTION OF 2,6-DIMETHYLNAPHTHALENE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1993-05-12 | — | — | EP | claimed |
| US-5023390-A | Process for production of 2,6-dimethylnaphthalene | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-06-11 | — | — | US | claimed |
| EP-0362651-A2 | Process for the production of 2,6-dimethylnaphthalene | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-04-11 | — | — | EP | claimed |
| US-4057646-A | Substituted or unsubstituted p-alkanoyl toluenes as male anti-fertility agents | SANDOZ, INC. (US) | 1977-11-08 | — | — | US | claimed |
| US-3968247-A | Substituted or unsubstituted p-alkanoyl toluenes as anti-diabetic agents | SANDOZ, INC. (US) | 1976-07-06 | — | — | US | claimed |
| US-3962342-A | Bromination process | SANDOZ, INC. (US) | 1976-06-08 | — | — | US | claimed |
| US-3941888-A | Substituted or unsubstituted p-alkanoyl toluenes as hypolipidemics | SANDOZ, INC. (US) | 1976-03-02 | — | — | US | claimed |
| JP-2096540-A | — | — | None | — | — | JP | disclosed |
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230357302-A1 | TRITERPENE SAPONIN VARIANTS, METHODS OF SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2023-11-09 | — | — | US | disclosed |
| US-11796914-B2 | Photosensitive resin structure for printing plate, and method for producing same | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-10-24 | — | — | US | disclosed |
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |
| US-3996286-A | HYPOLIPIDEMIC AGENTS, HYPOCHOLESTEROLEMICS | SANDOZ, INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3978132-A | HYPOLIPIDEMIC | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |
| US-3968247-A | Substituted or unsubstituted p-alkanoyl toluenes as anti-diabetic agents | SANDOZ, INC. (US) | 1976-07-06 | — | — | US | disclosed |
| US-3962342-A | Bromination process | SANDOZ, INC. (US) | 1976-06-08 | — | — | US | disclosed |
| US-3962342-A | Bromination process | SANDOZ, INC. (US) | 1976-06-08 | — | — | US | disclosed |
| US-3962320-A | HYPOLIPIDEMIC AGENTS | SANDOZ, INC. (US) | 1976-06-08 | — | — | US | disclosed |
| US-3941888-A | Substituted or unsubstituted p-alkanoyl toluenes as hypolipidemics | SANDOZ, INC. (US) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | TRIM33, TRIM28, TRIM4 | CA2 4633/4885ALDH1A1 3246/4885CES2 3614/4885 |
| US-20230357302-A1 | TRITERPENE SAPONIN VARIANTS, METHODS OF SYNTHESIS AND USE THEREOF | LSS, GALE, CYP4A11 | CA2 4407/4885ALDH1A1 4420/4885CES2 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.