Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778823 | 0.86 | MAPT (0.58) | MAPTLMNAGAAL3MBTL1ALDH3A1 | |
| SCHEMBL11780330 | 0.84 | MEN1 (0.47) | PKMMAPTLMNAGAAKMT2A | |
| SCHEMBL11780362 | 0.83 | PKM (0.65) | PKMMAPTLMNAL3MBTL1TDP1 | |
| SCHEMBL11783509 | 0.83 | MAPT (0.60) | MAPTLMNAGAAL3MBTL1ALDH3A1 | |
| SCHEMBL11852448 | 0.82 | HCAR3 (0.54) | MAPTLMNAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL11780536 | 0.80 | BDKRB1 (0.41) | PKMLMNAGAAL3MBTL1ALDH1A1 | |
| SCHEMBL11846360 | 0.80 | PKM (0.60) | PKMMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL11777201 | 0.76 | GAA (0.45) | MAPTLMNAGAAL3MBTL1ALDH1A1 | |
| SCHEMBL2883308 | 0.74 | HCAR3 (0.55) | MAPTLMNAALDH1A1TDP1KMT2A | |
| SCHEMBL11783471 | 0.73 | MEN1 (0.53) | MAPTLMNAGAAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |