Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242128 | 0.93 | SIGMAR1 (0.51) | HTR1ASLC6A4HTR7KCNH2 | |
| SCHEMBL7282326 | 0.82 | HTR1A (0.47) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| SCHEMBL11333398 | 0.81 | DRD2 (0.76) | DRD2DRD4DRD3HTR2ACHRNA7 | |
| SCHEMBL11346132 | 0.81 | ALDH1A1 (0.51) | — | |
| SCHEMBL11785874 | 0.80 | KCNH2 (0.61) | DRD2DRD4DRD3HTR2AHTR1A | |
| SCHEMBL27816761 | 0.80 | MPO (0.61) | HTR2AHTR1ASLC6A4HTR7KCNH2 | |
| SCHEMBL11783437 | 0.80 | DRD2 (0.70) | DRD2HTR2ACHRNA7HTR1AKCNH2 | |
| SCHEMBL11351695 | 0.79 | HTR1A (0.60) | HTR1A | |
| SCHEMBL11243420 | 0.79 | HTR1A (0.69) | HTR1A | |
| Hydrochloric Acid SCHEMBL11335313 | 0.79 | DRD2 (0.69) | DRD2HTR2ACHRNA7HTR1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE28973-E | PARKINSON'S DISEASE | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-09-21 | — | — | US | claimed |
| US-RE28973-E | PARKINSON'S DISEASE | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-09-21 | — | — | US | disclosed |