Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMPD2 | Q01433 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836908 | 0.85 | ACHE (0.42) | AMPD2DRD2DRD4HTTALDH1A1 | |
| SCHEMBL9073520 | 0.83 | AMPD2 (0.49) | AMPD2DRD2DRD4CRHBPCRHR2 | |
| SCHEMBL11786097 | 0.82 | DRD2 (0.58) | AMPD2DRD2DRD4HTTCRHBP | |
| SCHEMBL11783262 | 0.80 | AMPD2 (0.50) | AMPD2DRD2DRD4KDM4ECRHBP | |
| SCHEMBL9155272 | 0.79 | CRHBP (0.48) | DRD2DRD4KDM4EHTTALDH1A1 | |
| SCHEMBL3975558 | 0.78 | CRHBP (0.47) | DRD2DRD4KDM4EHTTALDH1A1 | |
| SCHEMBL11419734 | 0.77 | CRHBP (0.47) | AMPD2DRD2DRD4KDM4EHTT | |
| SCHEMBL11835343 | 0.76 | DRD2 (0.45) | AMPD2DRD2DRD4CRHBPCRHR2 | |
| SCHEMBL9636500 | 0.76 | CRHBP (0.43) | DRD2DRD4ALDH1A1CRHBPCRHR2 | |
| SCHEMBL11676845 | 0.76 | TSHR (0.44) | DRD2DRD4KDM4EHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000141-A | SUBSTITUTED TETRAHYDRO QUINOLINE CATIONIC DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
| US-3991042-A | Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | disclosed |