Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | AMPD2 | Q01433 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835343 | 0.88 | DRD2 (0.45) | DRD2DRD4AMPD2CRHBPCRHR2 | |
| SCHEMBL9073520 | 0.84 | AMPD2 (0.49) | DRD2DRD4AMPD2CRHBPCRHR2 | |
| SCHEMBL11786097 | 0.83 | DRD2 (0.58) | DRD2DRD4AMPD2NPSR1CRHBP | |
| SCHEMBL11783262 | 0.83 | AMPD2 (0.50) | DRD2DRD4AMPD2KDM4EMEN1 | |
| SCHEMBL11679920 | 0.81 | HRH3 (0.41) | DRD2DRD4KDM4EALDH1A1MAPT | |
| SCHEMBL11676378 | 0.78 | LTA4H (0.52) | — | |
| SCHEMBL11428861 | 0.77 | CRHBP (0.45) | DRD2DRD4KDM4EALDH1A1MAPT | |
| SCHEMBL11680703 | 0.77 | DRD2 (0.45) | DRD2DRD4LMNASMN1; SMN2 | |
| SCHEMBL3975558 | 0.77 | CRHBP (0.47) | DRD2DRD4KDM4EALDH1A1MAPT | |
| SCHEMBL10887269 | 0.76 | CRHBP (0.40) | DRD2DRD4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000141-A | SUBSTITUTED TETRAHYDRO QUINOLINE CATIONIC DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |