Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391427 | 0.92 | CYP3A4 (0.45) | CTSBCTSKCTSLCAPN1CCR1 | |
| SCHEMBL10357140 | 0.88 | CTSB (0.53) | CTSBCTSKCTSLCAPN1CCR1 | |
| SCHEMBL4425151 | 0.88 | CTSB (0.53) | CTSBCTSKCTSLCAPN1CCR1 | |
| SCHEMBL4039888 | 0.88 | CTSB (0.53) | CTSBCTSKCTSLCAPN1CCR1 | |
| SCHEMBL20529553 | 0.88 | CTRB1 (0.48) | CTSBCTSKCTSLCASP1CASP3 | |
| SCHEMBL25933042 | 0.84 | CYP3A4 (0.48) | CTSBCTSKCTSLCAPN1CCR1 | |
| SCHEMBL7325002 | 0.84 | CASP1 (0.46) | CTSBCTSKCTSLCCNE1CDK2 | |
| SCHEMBL11519751 | 0.84 | CYP3A4 (0.45) | CTSBCTSKCTSLCAPN1CCNE1 | |
| SCHEMBL6611310 | 0.83 | TRPM8 (0.56) | CTSBCTSKCTSLCYP3A4CYP2D6 | |
| SCHEMBL3221965 | 0.83 | CTSL (0.52) | CTSBCTSKCTSLCAPN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3971822-A | Aspartyl amide sweetening agents | TANABE SEIYAKU CO., LTD. (JA) | 1976-07-27 | — | — | US | disclosed |