Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.53 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 4/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.51 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039888 | 1.00 | CTSB (0.53) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL10357140 | 1.00 | CTSB (0.53) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL20529553 | 0.93 | CTRB1 (0.48) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL25933042 | 0.92 | CYP3A4 (0.48) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL2579674 | 0.90 | CYP3A4 (0.62) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL10345811 | 0.88 | CTSK (0.50) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL14366653 | 0.88 | CTSK (0.50) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL4432276 | 0.88 | CTSK (0.50) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL11799985 | 0.88 | CTSB (0.47) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL11519751 | 0.87 | CYP3A4 (0.45) | CTSBCTSKCTSLCTSSCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4748843-A2 | ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Medilink Therapeutics (Suzhou) Co., Ltd. (CN) | 2026-05-27 | — | — | EP | disclosed |
| EP-4725560-A2 | ANTI-B7H3 ANTIBODIES FOR THE PREPARATION OF ANTIBODY DRUG CONJUGATES (ADCS) OF KSP INHIBITORS | Bayer Pharma Aktiengesellschaft (DE) | 2026-04-15 | — | — | EP | disclosed |
| EP-4673474-A2 | ANTI-PSMA ANTIBODIES, CONJUGATES, AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2026-01-07 | — | — | EP | disclosed |
| EP-4619037-A1 | SMALL MOLECULE-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT | Lerchen, Hans-Georg (DE) | 2025-09-24 | — | — | EP | disclosed |
| US-20250242034-A1 | PHOSPHORAMIDATE-BASED PSMA-TARGETED SMALL-MOLECULE DRUG CONJUGATES | CANCER TARGETED TECH LLC (US) | 2025-07-31 | — | — | US | disclosed |
| EP-4552654-A1 | ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Medilink Therapeutics (Suzhou) Co., Ltd. (CN) | 2025-05-14 | — | — | EP | disclosed |
| US-20250099600-A1 | Active Metabolites of Kinesin Spindle Protein Inhibitor Conjugates | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2025-03-27 | — | — | US | disclosed |
| EP-4472668-A1 | PHOSPHORAMIDATE-BASED PSMA-TARGETED SMALL-MOLECULE DRUG CONJUGATES | Cancer Targeted Technology LLC (US) | 2024-12-11 | — | — | EP | disclosed |
| WO-2024242629-A1 | MOLECULAR RADIOAFTERGLOW PROBES FOR CANCER RADIODYNAMIC THERANOSTICS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-11-28 | — | — | WO | disclosed |
| US-12144865-B2 | Antibody drug conjugates with enzymatically cleavable groups | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2024-11-19 | — | — | US | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0480044-A1 | NOVEL 4H-3,1-BENZOXAZIN-4-ONE DERIVATIVE | Japan Tobacco Inc. (JP) | 1992-04-15 | — | — | EP | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0167152-B1 | PROTEASE ADSORBENT AND PROCESS FOR PURIFYING TPA UTILIZING THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-11-14 | — | — | EP | disclosed |
| US-4708944-A | Protease adsorbent and process for purifying TPA utilizing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1987-11-24 | — | — | US | disclosed |
| EP-0167152-A2 | Protease adsorbent and process for purifying TPA utilizing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1986-01-08 | — | — | EP | disclosed |
| US-4341707-A | CHEMICAL INTERMEDIATES; PEPTIDE SYNTHESIS | Ogura, Haruo (JP) | 1982-07-27 | — | — | US | disclosed |
| US-4250085-A | PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | disclosed |
| EP-0002822-A1 | Phosphorus containing peptide derivatives, their production, intermediates for their production and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-07-11 | — | — | EP | disclosed |
| US-4064270-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250242034-A1 | PHOSPHORAMIDATE-BASED PSMA-TARGETED SMALL-MOLECULE DRUG CONJUGATES | FOLH1, KLK3, ACP3 | CTSB 447/4885CTSK 754/4885CTSL 755/4885 |
| US-20250099600-A1 | Active Metabolites of Kinesin Spindle Protein Inhibitor Conjugates | KIF18B, KIF18A, KIF5B | CTSB 3255/4885CTSK 2951/4885CTSL 3462/4885 |
| US-12144865-B2 | Antibody drug conjugates with enzymatically cleavable groups | KIFC1, KIF2C, KIF5B | CTSB 1614/4885CTSK 1510/4885CTSL 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.