Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 5/20 | 0.44 |
| ▸ | CTSB | P07858 | 5/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 6/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039888 | 0.85 | CTSB (0.53) | CASP1CTSLCTSBCTSSELANE | |
| SCHEMBL10357140 | 0.85 | CTSB (0.53) | CASP1CTSLCTSBCTSSELANE | |
| SCHEMBL4425151 | 0.85 | CTSB (0.53) | CASP1CTSLCTSBCTSSELANE | |
| SCHEMBL11799985 | 0.84 | CTSB (0.47) | CASP1CCNE1CDK2GSK3BSYK | |
| SCHEMBL7391427 | 0.84 | CYP3A4 (0.45) | CASP1CCNE1CDK2GSK3BSYK | |
| SCHEMBL10345811 | 0.84 | CTSK (0.50) | CASP1CTSLCTSBCTSSELANE | |
| SCHEMBL4432276 | 0.84 | CTSK (0.50) | CASP1CTSLCTSBCTSSELANE | |
| SCHEMBL14366653 | 0.84 | CTSK (0.50) | CASP1CTSLCTSBCTSSELANE | |
| SCHEMBL20529553 | 0.84 | CTRB1 (0.48) | CASP1CTSLCTSBCTSSATM | |
| SCHEMBL5972712 | 0.83 | CASP1 (0.46) | CASP1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594656-A1 | 4-AMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES | SANDOZ LTD. (CH) | 1994-05-04 | — | — | EP | disclosed |
| WO-1993001166-A1 | 4-AMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES | SANDOZ LTD. (CH) | 1993-01-21 | — | — | WO | disclosed |