Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818479 | 0.88 | CA2 (0.46) | ALDH1A1MEN1KMT2ACA2CA4 | |
| SCHEMBL11820018 | 0.85 | CA2 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11821785 | 0.84 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11821491 | 0.84 | MEN1 (0.45) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11818248 | 0.84 | CA2 (0.43) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL11816258 | 0.83 | CYP1A2 (0.46) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11828522 | 0.82 | MEN1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11821210 | 0.81 | MEN1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11817917 | 0.78 | PTPRG (0.47) | MEN1KMT2APOLBLMNACA2 | |
| SCHEMBL11817140 | 0.78 | CA2 (0.42) | ALDH1A1MEN1KMT2ACA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |