Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824107 | 0.89 | CA2 (0.53) | CA2CA4ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL11821552 | 0.88 | CA2 (0.42) | CA2CA4ALDH1A1LMNAHTT | |
| SCHEMBL11843840 | 0.87 | ALDH1A1 (0.46) | CA2CA4ALDH1A1LMNAHTT | |
| SCHEMBL11838590 | 0.87 | LMNA (0.40) | POLBCA2CA4ALDH1A1LMNA | |
| SCHEMBL11819726 | 0.85 | LMNA (0.45) | POLBCA2CA4METAP2ALDH1A1 | |
| SCHEMBL11821697 | 0.85 | ALDH1A1 (0.49) | POLBCA2CA4ALDH1A1HTT | |
| SCHEMBL11820483 | 0.84 | TAS2R14 (0.61) | CA2CA4TAS2R14 | |
| SCHEMBL11825881 | 0.84 | TAS2R14 (0.43) | POLBCA2CA4ALDH1A1LMNA | |
| SCHEMBL11816329 | 0.84 | CNR2 (0.49) | POLBCA2METAP2ALDH1A1LMNA | |
| SCHEMBL11817200 | 0.81 | ALDH1A1 (0.53) | CA2CA4ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |