Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11838590 | 0.89 | LMNA (0.40) | ALDH1A1KDM4EPTPN1CA2CA4 | |
| SCHEMBL11818509 | 0.87 | POLB (0.45) | ALDH1A1KDM4ECA2CA4LMNA | |
| SCHEMBL11824107 | 0.86 | CA2 (0.53) | ALDH1A1KDM4ECA2MEN1KMT2A | |
| SCHEMBL11821552 | 0.85 | CA2 (0.42) | ALDH1A1KDM4ECA2CA4LMNA | |
| SCHEMBL11814899 | 0.85 | PPARD (0.43) | BCHEACHEPPARDCA2CA4 | |
| SCHEMBL11821697 | 0.82 | ALDH1A1 (0.49) | ALDH1A1BCHEACHECA2MEN1 | |
| SCHEMBL11818557 | 0.81 | FKBP1A (0.47) | ALDH1A1KDM4EBCHEACHEPPARD | |
| SCHEMBL11817200 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4ECA2MEN1KMT2A | |
| SCHEMBL11853927 | 0.78 | TRPV4 (0.45) | ALDH1A1TRPV4BCHEACHEPPARD | |
| SCHEMBL11817253 | 0.78 | PTPRG (0.52) | CA2MEN1KMT2ACA4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |