Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTPRG | P23470 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817200 | 0.89 | ALDH1A1 (0.53) | CA2CA4ALDH1A1NPC1RAB9A | |
| SCHEMBL11818509 | 0.89 | POLB (0.45) | CA2CA4ALDH1A1NPC1RAB9A | |
| SCHEMBL11821552 | 0.89 | CA2 (0.42) | CA2CA4ALDH1A1NPC1RAB9A | |
| SCHEMBL11820863 | 0.88 | KMT2A (0.48) | CA2CA4ALDH1A1NPC1RAB9A | |
| SCHEMBL11817253 | 0.88 | PTPRG (0.52) | CA2CA4NPC1RAB9ATNF | |
| SCHEMBL11817412 | 0.86 | CA2 (0.52) | CA2CA4ALDH1A1HPGDKMT2A | |
| SCHEMBL11821697 | 0.86 | ALDH1A1 (0.49) | CA2CA4ALDH1A1RAB9AKMT2A | |
| SCHEMBL11838590 | 0.86 | LMNA (0.40) | CA2CA4ALDH1A1NPC1RAB9A | |
| SCHEMBL11843840 | 0.86 | ALDH1A1 (0.46) | CA2CA4ALDH1A1KDM4EKMT2A | |
| SCHEMBL11820805 | 0.84 | CA2 (0.48) | CA2CA4ALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |