Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTPRG | P23470 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824107 | 0.89 | CA2 (0.53) | CA2CA4LMNANPC1KDM4E | |
| SCHEMBL11818509 | 0.88 | POLB (0.45) | CA2CA4LMNANPC1KDM4E | |
| SCHEMBL11823574 | 0.85 | MAPT (0.44) | CA2CA4LMNAKDM4EHTT | |
| SCHEMBL11838590 | 0.85 | LMNA (0.40) | CA2CA4LMNANPC1KDM4E | |
| SCHEMBL11821697 | 0.85 | ALDH1A1 (0.49) | CA2CA4HTTALDH1A1RAB9A | |
| SCHEMBL11843840 | 0.85 | ALDH1A1 (0.46) | CA2CA4LMNAKDM4EHTT | |
| SCHEMBL11819740 | 0.84 | VCAM1 (0.40) | CA2CA4LMNAKDM4EHTT | |
| SCHEMBL11823057 | 0.84 | ALDH1A1 (0.41) | CA2CA4ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11817200 | 0.81 | ALDH1A1 (0.53) | CA2CA4NPC1KDM4EALDH1A1 | |
| SCHEMBL11817140 | 0.81 | CA2 (0.42) | CA2CA4ALDH1A1PTPRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |