Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828512 | 0.78 | TDP1 (0.37) | KDM4EGAASMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL11836007 | 0.78 | TDP1 (0.32) | XPO1L3MBTL1TDP1 | |
| SCHEMBL7749356 | 0.77 | MAPT (0.38) | KDM4EGAASMN1; SMN2CASP1HSD17B10 | |
| SCHEMBL11832348 | 0.76 | MAPT (0.40) | TSHRKMT2ACETPMAPT | |
| SCHEMBL11259430 | 0.76 | RXRA (0.38) | KDM4EGAASMN1; SMN2HSD17B10TSHR | |
| SCHEMBL11836012 | 0.74 | L3MBTL1 (0.33) | KDM4EGAACASP1HSD17B10L3MBTL1 | |
| SCHEMBL7749357 | 0.73 | MAPT (0.35) | GAASMN1; SMN2CASP1HSD17B10L3MBTL1 | |
| SCHEMBL11818519 | 0.72 | ALDH1A1 (0.47) | SMN1; SMN2CASP1HSD17B10L3MBTL1KMT2A | |
| SCHEMBL28985335 | 0.71 | LMNA (0.47) | KDM4EGAASMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL11263347 | 0.71 | FFAR1 (0.38) | KDM4EGAASMN1; SMN2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3979444-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS, HYPOTENSIVES | THE UPJOHN COMPANY (US) | 1976-09-07 | — | — | US | disclosed |