Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Urea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL28657901 | 0.94 | — | — | |
| Urea SCHEMBL10800447 | 0.89 | LMNA (0.60) | — | |
| Carbamic Acid SCHEMBL10799327 | 0.89 | ACHE (0.70) | — | |
| Urea SCHEMBL27751537 | 0.88 | — | — | |
| Urea SCHEMBL10413304 | 0.88 | — | — | |
| Urea SCHEMBL28191757 | 0.88 | — | — | |
| Urea SCHEMBL16027134 | 0.88 | — | — | |
| Urea SCHEMBL225908 | 0.88 | — | — | |
| Urea SCHEMBL7756359 | 0.87 | LMNA (1.00) | — | |
| Urea SCHEMBL8434002 | 0.87 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112852023-A | Preparation method of biomass high-dielectric nano composite film | 武汉理工大学 | 2021-05-28 | — | — | CN | claimed |
| CN-109503786-B | Urea-formaldehyde resin, preparation method thereof and degradable mulching film prepared from urea-formaldehyde resin | 太尔胶粘剂(广东)有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-111690075-B | Water-soluble beta-glucan, preparation method thereof and application thereof in preparation of immune enhancement and anti-tumor medicines and health-care products | 中国海洋大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-112852023-A | Preparation method of biomass high-dielectric nano composite film | 武汉理工大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-112852023-A | Preparation method of biomass high-dielectric nano composite film | 武汉理工大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-111690075-A | Water-soluble beta-glucan, preparation method thereof and application thereof in preparation of immune enhancement and anti-tumor medicines and health-care products | 中国海洋大学 | 2020-09-22 | — | — | CN | disclosed |
| US-3935300-A | Process for preparing potassium cyanate from potassium hydroxide and urea | MISSISSIPPI CHEMICAL CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |