Urea

Urea

SCHEMBL28657901

NC(N)=O.[K+].[Na+].[OH-].[OH-]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Urea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL11833338 0.94
Urea SCHEMBL225908 0.94
Urea SCHEMBL28427765 0.89
Urea SCHEMBL10800447 0.84 LMNA (0.60)
Carbamic Acid SCHEMBL10799327 0.84 ACHE (0.70)
Carbamic Acid SCHEMBL10800569 0.84 ACHE (0.70)
Urea SCHEMBL28180087 0.84
Urea SCHEMBL10800403 0.84 LMNA (0.60)
Urea SCHEMBL2240218 0.82
Urea SCHEMBL16027134 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111690075-B Water-soluble beta-glucan, preparation method thereof and application thereof in preparation of immune enhancement and anti-tumor medicines and health-care products 中国海洋大学 2021-10-15 CN disclosed
CN-111690075-A Water-soluble beta-glucan, preparation method thereof and application thereof in preparation of immune enhancement and anti-tumor medicines and health-care products 中国海洋大学 2020-09-22 CN disclosed