Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354626 | 1.00 | PIK3CA (0.44) | PIK3CADAOPNMTTAAR1HDAC3 | |
| SCHEMBL27814750 | 0.83 | TAAR1 (0.45) | PIK3CADAOPNMTTAAR1HDAC3 | |
| SCHEMBL29357072 | 0.82 | CYP4F2 (0.42) | PNMTTAAR1CYP4F2CYP4A11MAPT | |
| SCHEMBL119714 | 0.82 | CYP4F2 (0.42) | PNMTTAAR1CYP4F2CYP4A11MAPT | |
| SCHEMBL79509 | 0.79 | DAO (0.43) | PIK3CADAOPNMTTAAR1HDAC3 | |
| SCHEMBL1503218 | 0.79 | PIK3CA (0.45) | PIK3CADAOPNMTTAAR1HDAC3 | |
| SCHEMBL16388285 | 0.79 | PIK3CA (0.45) | PIK3CADAOPNMTTAAR1HDAC3 | |
| SCHEMBL29410646 | 0.78 | HTT (0.47) | DAOALDH1A1HTTNPSR1TSHR | |
| SCHEMBL10128 | 0.78 | IDO1 (0.58) | PNMTTAAR1CYP4F2CYP4A11SLC6A4 | |
| SCHEMBL29413271 | 0.78 | IDO1 (0.58) | PNMTTAAR1CYP4F2CYP4A11SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634487-B | Preparation method of quinoline feed additive with immunity improving function | 河南湾流生物科技有限公司 | 2024-08-13 | — | — | CN | claimed |
| CN-114634487-A | Preparation method of quinoline feed additive with function of improving immunity | 河南湾流生物科技有限公司 | 2022-06-17 | — | — | CN | claimed |
| EP-4692085-A2 | PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS | Nxera Pharma UK Limited (GB) | 2026-02-11 | — | — | EP | disclosed |
| EP-4663640-A1 | XANTHINE COMPOUND AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2025-12-17 | — | — | EP | disclosed |
| US-20250376443-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-12-11 | — | — | US | disclosed |
| US-20250368604-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-12-04 | — | — | US | disclosed |
| US-12486278-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2025-12-02 | — | — | US | disclosed |
| EP-4041388-B1 | PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS | NXERA PHARMA UK LTD (GB) | 2025-11-26 | — | — | EP | disclosed |
| US-20250340557-A1 | PYRIMIDINE DERIVATIVE | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2025-11-06 | — | — | US | disclosed |
| EP-3768269-B1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-20 | — | — | EP | disclosed |
| EP-4553068-A1 | PYRIMIDINE DERIVATIVES | ASKA Pharmaceutical Co., Ltd. (JP) | 2025-05-14 | — | — | EP | disclosed |
| WO-2000046196-A1 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ASTRAZENECA AB (SE) | 2000-08-10 | — | — | WO | disclosed |
| EP-1020441-A1 | N-HETEROCYCLIC METHYLPROPYLAMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND GERMICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |
| CN-1207731-A | 3-pyrazolecarboxamide derivs. having cannabinoid receptor affinity | SANOFI SA (FR) | 1999-02-10 | — | — | CN | disclosed |
| US-4282388-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-04 | — | — | US | disclosed |
| EP-0002214-B1 | BENZYL ETHERS OF CYCLIC 1,2-DIOLS, METHODS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1981-05-13 | — | — | EP | disclosed |
| EP-0002214-A1 | Benzyl ethers of cyclic 1,2-diols, methods for their preparation and their use as herbicides | BAYER AG (DE) | 1979-06-13 | — | — | EP | disclosed |
| US-4146384-A | Tetrahydrofuran-ether compounds and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |
| EP-0000002-A1 | Tetrahydrofurane derivatives, processes for their preparation and their use as herbicides | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12486278-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | PIK3CA 2529/4885DAO 3003/4885PNMT 3958/4885 |
| US-20250368604-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, METAP2, SPINT2 | PIK3CA 2503/4885DAO 2981/4885PNMT 3893/4885 |
| US-20250376443-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, METAP2, SPINT2 | PIK3CA 2662/4885DAO 2932/4885PNMT 3968/4885 |
| US-20250340557-A1 | PYRIMIDINE DERIVATIVE | PTGES, PTGS1, PTGIS | PIK3CA 2222/4885DAO 2573/4885PNMT 1338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.