Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4122825 | 0.83 | ADRB2 (0.50) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL2760850 | 0.82 | ADRA2A (0.66) | ADRB2HIF1AADRB1CYP2D6BLM | |
| SCHEMBL7317693 | 0.81 | ADRB2 (0.65) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL11850533 | 0.79 | ADRB1 (0.68) | ADRB2HIF1AADRB1NFKB1BLM | |
| Oxalic Acid SCHEMBL7311294 | 0.76 | ADRB1 (0.57) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL250026 | 0.75 | ADRB2 (0.65) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL120043 | 0.75 | ADRB2 (0.65) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL29508537 | 0.75 | ADRB2 (0.65) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL2250 | 0.74 | ADRA2A (0.61) | ADRB2HIF1AADRB1NFKB1BLM | |
| Tulobuterol SCHEMBL122692 | 0.72 | ADRB2 (1.00) | ADRB2HIF1AADRB1CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976695-A | Halogen substituted α-(aminoalkyl)-3,4-dihydroxybenzyl alcohols | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |