Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656974 | 0.94 | GLP1R (0.35) | SMN1; SMN2ALDH1A1MEP1BPTGDRJAK2 | |
| SCHEMBL11913427 | 0.93 | SMN1; SMN2 (0.37) | PTGESSMN1; SMN2ALDH1A1 | |
| SCHEMBL11903304 | 0.93 | ABCB11 (0.34) | PTGESSMN1; SMN2ALDH1A1MEP1BMTNR1A | |
| SCHEMBL1654723 | 0.88 | NR4A2 (0.36) | MEP1B | |
| SCHEMBL11903307 | 0.87 | PTGES (0.32) | PTGESSMN1; SMN2MEP1B | |
| SCHEMBL11902410 | 0.86 | SMN1; SMN2 (0.34) | PTGESSMN1; SMN2ALDH1A1MEP1BJAK2 | |
| SCHEMBL11903206 | 0.86 | PKM (0.35) | PTGESSMN1; SMN2L3MBTL1ALDH1A1MEP1B | |
| SCHEMBL11902585 | 0.85 | DHODH (0.39) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL11902294 | 0.84 | PTGES (0.33) | PTGESMEP1B | |
| SCHEMBL11902825 | 0.84 | KMO (0.43) | ALDH1A1MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | PTGES 1440/4885SMN1; SMN2 3709/4885L3MBTL1 2005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.