Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656974 | 0.90 | GLP1R (0.35) | ALDH1A1HPGDMEP1BSMN1; SMN2KMT2A | |
| SCHEMBL1654723 | 0.88 | NR4A2 (0.36) | PKMKDM4EMEP1BRXFP1PRKAB2 | |
| SCHEMBL11903304 | 0.86 | ABCB11 (0.34) | ALDH1A1KDM4EMEP1BSMN1; SMN2MAPK1 | |
| SCHEMBL11902297 | 0.86 | PTGES (0.36) | ALDH1A1L3MBTL1MEP1BSMN1; SMN2PTGES | |
| SCHEMBL11903329 | 0.85 | MEP1B (0.33) | ALDH1A1HSD17B10KDM4EHPGDMEP1B | |
| SCHEMBL11902585 | 0.85 | DHODH (0.39) | HSD17B10L3MBTL1SMN1; SMN2LMNATSHR | |
| SCHEMBL11903222 | 0.85 | SMN1; SMN2 (0.34) | PKMALDH1A1HSD17B10KDM4EMEP1B | |
| SCHEMBL11913427 | 0.84 | SMN1; SMN2 (0.37) | ALDH1A1KDM4EHPGDSMN1; SMN2NPC1 | |
| SCHEMBL11902825 | 0.84 | KMO (0.43) | ALDH1A1HSD17B10KDM4EMEP1BPRKAB2 | |
| SCHEMBL11903307 | 0.84 | PTGES (0.32) | MEP1BSMN1; SMN2MAPK1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | PKM 3536/4885ALDH1A1 718/4885HSD17B10 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.