Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.44 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.44 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.44 |
| ▸ | WNT3A | P56704 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31407204 | 0.83 | L3MBTL1 (0.56) | L3MBTL1CYP2C19ALDH1A1CYP1A2PLOD2 | |
| SCHEMBL8535125 | 0.82 | ALDH1A1 (0.61) | L3MBTL1CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL15988710 | 0.81 | CYP2C19 (0.61) | L3MBTL1CYP2C19ALDH1A1CYP1A2PLOD2 | |
| SCHEMBL27755450 | 0.79 | ALDH1A1 (0.52) | L3MBTL1CYP2C19ALDH1A1CYP1A2PLOD2 | |
| SCHEMBL9195700 | 0.74 | ALDH1A1 (0.77) | L3MBTL1CYP2C19ALDH1A1CYP1A2PLOD2 | |
| SCHEMBL10843960 | 0.74 | NR4A2 (0.65) | L3MBTL1CYP2C19ALDH1A1CYP1A2PLOD2 | |
| Propyl 4-Pyridyl Ketone SCHEMBL4952700 | 0.74 | HSD17B3 (0.61) | L3MBTL1CYP2C19ALDH1A1CYP1A2PLOD2 | |
| SCHEMBL6160053 | 0.72 | ALDH1A1 (0.48) | L3MBTL1CYP2C19ALDH1A1CYP1A2PLOD2 | |
| SCHEMBL15969141 | 0.72 | CTNNB1 (0.72) | CYP2C19ALDH1A1CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL7977170 | 0.72 | CTNNB1 (0.54) | L3MBTL1CYP2C19ALDH1A1CYP1A2PLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883827-B2 | Azole derivatives as WTN pathway inhibitors | OSLO UNIVERSITY HOSPITAL HF (NO) | 2014-11-11 | — | — | US | disclosed |
| US-8883827-B2 | Azole derivatives as WTN pathway inhibitors | OSLO UNIVERSITY HOSPITAL HF (NO) | 2014-11-11 | — | — | US | disclosed |
| US-20120208828-A1 | Azole Derivatives as WTN Pathway Inhibitors | OSLO UNIVERSITY HOSPITAL HF (NO) | 2012-08-16 | — | — | US | disclosed |
| US-20120208828-A1 | Azole Derivatives as WTN Pathway Inhibitors | OSLO UNIVERSITY HOSPITAL HF (NO) | 2012-08-16 | — | — | US | disclosed |
| WO-2010139966-A1 | AZOLE DERIVATIVES AS WTN PATHWAY INHIBITORS | OSLO UNIVERSITY HOSPITAL HF (NO) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208828-A1 | Azole Derivatives as WTN Pathway Inhibitors | WNT1, AXIN2, WNT3 | L3MBTL1 4716/4885CYP2C19 1047/4885ALDH1A1 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.